Difference between revisions of "FlhP"

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* '''Description:''' flagellar hook-basal body protein <br/><br/>
+
* '''Description:''' flagellar hook-basal body protein, required for hook assembly <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Product''' || flagellar hook-basal body protein
 
|style="background:#ABCDEF;" align="center"| '''Product''' || flagellar hook-basal body protein
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || movement and chemotaxis  
+
|style="background:#ABCDEF;" align="center"|'''Function''' || [[motility and chemotaxis]] 
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 29 kDa, 4.589   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 29 kDa, 4.589   
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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* lack of [[SigD]]-dependent gene expression (no ''[[hag]]'' expression), no motility  {{PubMed|22730131}}
  
 
=== Database entries ===
 
=== Database entries ===
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  
+
* '''Catalyzed reaction/ biological activity:''' assembly of the flagellar hook {{PubMed|22730131}}
  
 
* '''Protein family:''' flagella basal body rod proteins family (according to Swiss-Prot)
 
* '''Protein family:''' flagella basal body rod proteins family (according to Swiss-Prot)
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* '''Operon:'''  
 
* '''Operon:'''  
 
** ''[[usd]]-[[spoIIID]]-[[mbl]]-[[flhO]]-[[flhP]]'' {{PubMed|9023218,7836311}}  
 
** ''[[usd]]-[[spoIIID]]-[[mbl]]-[[flhO]]-[[flhP]]'' {{PubMed|9023218,7836311}}  
** ''[[flhO]]-[[flhP]]'' {{PubMed|15033535}}  
+
** ''[[flhO]]-[[flhP]]'' {{PubMed|15033535,22730131}}  
  
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=flhP_3745436_3746245_-1 flhP] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=flhP_3745436_3746245_-1 flhP] {{PubMed|22383849}}
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* '''Sigma factor:'''  
 
* '''Sigma factor:'''  
 
** ''[[usd]]'': [[SigE]] {{PubMed|9023218}}  
 
** ''[[usd]]'': [[SigE]] {{PubMed|9023218}}  
** ''[[flhO]]'': [[SigD]] {{PubMed|15033535}}  
+
** ''[[flhO]]'': [[SigD]] {{PubMed|15033535,22730131}}  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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=References=
 
=References=
 
+
'''Additional publications:''' {{PubMed|22730131}}
 
<pubmed>18957862,9023218 7836311 15033535</pubmed>
 
<pubmed>18957862,9023218 7836311 15033535</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 14:20, 27 June 2012

  • Description: flagellar hook-basal body protein, required for hook assembly

Gene name flhP
Synonyms yvyB
Essential no
Product flagellar hook-basal body protein
Function motility and chemotaxis
MW, pI 29 kDa, 4.589
Gene length, protein length 804 bp, 268 aa
Immediate neighbours rapD, flhO
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
FlhP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FlhP expression.png
























Categories containing this gene/protein

motility and chemotaxis

This gene is a member of the following regulons

SigD regulon

The gene

Basic information

  • Locus tag: BSU36390

Phenotypes of a mutant

  • lack of SigD-dependent gene expression (no hag expression), no motility PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: assembly of the flagellar hook PubMed
  • Protein family: flagella basal body rod proteins family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862] [WorldCat.org] [DOI] (I p)

Masakuni Serizawa, Hiroki Yamamoto, Hirotake Yamaguchi, Yasutaro Fujita, Kazuo Kobayashi, Naotake Ogasawara, Junichi Sekiguchi
Systematic analysis of SigD-regulated genes in Bacillus subtilis by DNA microarray and Northern blotting analyses.
Gene: 2004, 329;125-36
[PubMed:15033535] [WorldCat.org] [DOI] (P p)

A Decatur, M T McMurry, B N Kunkel, R Losick
Translation of the mRNA for the sporulation gene spoIIID of Bacillus subtilis is dependent upon translation of a small upstream open reading frame.
J Bacteriol: 1997, 179(4);1324-8
[PubMed:9023218] [WorldCat.org] [DOI] (P p)

Y Abhayawardhane, G C Stewart
Bacillus subtilis possesses a second determinant with extensive sequence similarity to the Escherichia coli mreB morphogene.
J Bacteriol: 1995, 177(3);765-73
[PubMed:7836311] [WorldCat.org] [DOI] (P p)