Difference between revisions of "Rok"
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* '''Operon:''' ''rok'' {{PubMed|12354229}} | * '''Operon:''' ''rok'' {{PubMed|12354229}} | ||
| − | * '''[ | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rok_1493787_1494362_1 rok] {{PubMed|22383849}} |
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| + | * '''Sigma factor:''' | ||
* '''Regulation:''' | * '''Regulation:''' | ||
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** [[AbrB]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/11849533 PubMed] | ** [[AbrB]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/11849533 PubMed] | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 08:00, 13 April 2012
- Description: repressor of comK, nucleoid associated protein that serves to help repress expression of A+T-rich genes, many of which appear to have been acquired by horizontal gene transfer
| Gene name | rok |
| Synonyms | ykuW |
| Essential | no |
| Product | transcriptional repressor |
| Function | regulation of genetic competence |
| Metabolic function and regulation of this protein in SubtiPathways: Protein secretion | |
| MW, pI | 21 kDa, 9.701 |
| Gene length, protein length | 573 bp, 191 aa |
| Immediate neighbours | ykuV, yknT |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
genetic competence, transcription factors and their control
This gene is a member of the following regulons
AbrB regulon, Rok regulon, SinR regulon, Spo0A regulon
The Rok regulon
The gene
Basic information
- Locus tag: BSU14240
Phenotypes of a mutant
higher excision rate of the conjugative transposon ICEBs1 PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: binds to extended regions of the B. subtilis genome that are characterized by a high A+T content and are known or believed to have been acquired by horizontal gene transfer PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34857
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: rok PubMed
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original Publications
Additional publications: PubMed
