Difference between revisions of "CmpA"

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(Created page with "* '''Description:''' spore coat protein <br/><br/> {| align="right" border="1" cellpadding="2" |- |style="background:#ABCDEF;" align="center"|'''Gene name''' |''cmpA'' |- |styl...")
 
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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
 
{{SubtiWiki regulon|[[SigE regulon]]}},
 
{{SubtiWiki regulon|[[SigE regulon]]}},
{{SubtiWiki regulon|[[SigK regulon]]}}
+
{{SubtiWiki regulon|[[SpoIIID regulon]]}}
  
 
=The gene=
 
=The gene=
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=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:''' BSU17030
+
* '''Locus tag:''' not available
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
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=== Database entries ===
 
=== Database entries ===
  
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/cotE.html]
+
* '''DBTBS entry:''' no entry
  
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10494]
+
* '''SubtiList entry:''' no entry
  
 
=== Additional information===
 
=== Additional information===
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:''' assembly of the [[CotC]]-[[CotU]] complex {{PubMed|20023017,18065538}}
+
* '''Catalyzed reaction/ biological activity:'''  
  
* '''Protein family:''' cotE family (according to Swiss-Prot)
+
* '''Protein family:'''  
  
 
* '''Paralogous protein(s):'''
 
* '''Paralogous protein(s):'''
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* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
** homotypic interaction [http://www.ncbi.nlm.nih.gov/sites/entrez/19304857 PubMed]
 
** [[CotE]]-[[CotC]] {{PubMed|20023017}}
 
** [[CotE]]-[[CotU]] {{PubMed|20023017}}
 
  
 
* '''[[Localization]]:'''  
 
* '''[[Localization]]:'''  
** encircles the forespore with a biased accumulation on the mother cell-proximal face of the forespore {{PubMed|22463703}}
+
** surface of the developing spore {{PubMed|22463703}}
 +
 
 
=== Database entries ===
 
=== Database entries ===
  
 
* '''Structure:'''
 
* '''Structure:'''
  
* '''UniProt:''' [http://www.uniprot.org/uniprot/P14016 P14016]
+
* '''UniProt:'''  
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU17030]
+
* '''KEGG entry:'''  
  
 
* '''E.C. number:'''
 
* '''E.C. number:'''
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:''' ''[[cotE]]'' {{PubMed|8760914}}
+
* '''Operon:''' ''[[cmpA]]'' {{PubMed|22463703}}
  
* '''[[Sigma factor]]:''' [[SigE]] {{PubMed|15699190,1691789}}, [[SigK]] {{PubMed|1691789}}
+
* '''[[Sigma factor]]:''' [[SigE]] {{PubMed|22463703}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
** repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed]
+
** expressed early during sporulation in the mother cell ([[SigE]]) {{PubMed|22463703}}
** expressed during sporulation in the mother cell ([[SigE]], [[SigK]]) {{PubMed|1691789}}
 
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[SpoIIID]]: transcription activation {{PubMed|22463703}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''

Revision as of 16:39, 11 April 2012

  • Description: spore coat protein

Gene name cmpA
Synonyms
Essential no
Product cortex morphogenetic protein A
Function
MW, pI
Gene length, protein length 111 bp, 37 aa
Immediate neighbours ydcI, ydcK
Get the DNA and protein sequences
(Ebmeier et al., 2012)
Genetic context



Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigE regulon, SpoIIID regulon

The gene

Basic information

  • Locus tag: not available

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: no entry

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • UniProt:
  • KEGG entry:
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed early during sporulation in the mother cell (SigE) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Arthur Aronson, Purdue University, West Lafayette, USA homepage

Adriano Henriques, Lisbon, Portugal homepage

Your additional remarks

References

Additional publications: PubMed

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