Difference between revisions of "RecR"

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m (Reverted edits by 134.76.70.252 (talk) to last revision by Jstuelk)
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* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
 +
** [[RecR]]-[[RecO]],  [[RecR]]:[[RecO]] molecular ratio of 2:1 (as judged from other bacteria  such as ''E. coli'' and ''Deinococcus radiodurans'') {{PubMed|17581636}}
  
 
* '''[[Localization]]:'''  
 
* '''[[Localization]]:'''  
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* '''Structure:'''
 
* '''Structure:'''
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** [http://www.rcsb.org/pdb/explore/explore.do?structureId=2V1C 2V1C] (the [[RecR]]-[[RecO]] complex from ''Deinococcus radiodurans'', [[RecR]]: 52% identity, 78% similarity, [[RecO]]: 30%/ 58%)  {{PubMed|17581636}}
  
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/P24277 P24277]
 
* '''UniProt:''' [http://www.uniprot.org/uniprot/P24277 P24277]
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=References=
 
=References=
  
<pubmed>12884008,, 16479537 </pubmed>
+
<pubmed>12884008,17581636, 16479537 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 15:11, 6 March 2012

  • Description: repair, recombination

Gene name recR
Synonyms recM
Essential no
Product unknown
Function repair, recombination
MW, pI 21 kDa, 5.301
Gene length, protein length 594 bp, 198 aa
Immediate neighbours yaaK, yaaL
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RecR context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

DNA repair/ recombination

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU00210

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: recR family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Joanna Timmins, Ingar Leiros, Sean McSweeney
Crystal structure and mutational study of RecOR provide insight into its mode of DNA binding.
EMBO J: 2007, 26(13);3260-71
[PubMed:17581636] [WorldCat.org] [DOI] (P p)

Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537] [WorldCat.org] [DOI] (P p)

G Hambraeus, C von Wachenfeldt, L Hederstedt
Genome-wide survey of mRNA half-lives in Bacillus subtilis identifies extremely stable mRNAs.
Mol Genet Genomics: 2003, 269(5);706-14
[PubMed:12884008] [WorldCat.org] [DOI] (P p)