AlbA

• Description: radical S-adenosylmethionine enzyme, antilisterial bacteriocin (subtilosin) production
  
  

Gene name	albA
Synonyms	ywiA
Essential	no
Product	radical S-adenosylmethionine enzyme
Function	antilisterial bacteriocin (subtilosin) production
MW, pI	51 kDa, 6.195
Gene length, protein length	1344 bp, 448 aa
Immediate neighbours	sboX, albB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

miscellaneous metabolic pathways, biosynthesis of antibacterial compounds

This gene is a member of the following regulons

AbrB regulon, ResD regulon, Rok regulon

The gene

Basic information

• Locus tag: BSU37370

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • catalyzes thioether bond formation in subtilosin A PubMed
• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s): contains two [4Fe-4S] clusters PubMed

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P71011

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: sboA-sboX-albA-albB-albC-albD-albE-albF-albG PubMed

• Sigma factor: SigA PubMed PubMed

• Regulation:
  • repressed by Rok PubMed
  • expressed under anaerobic conditions (ResD) PubMed
  • repressed during logrithmic growth (AbrB) PubMed

• Regulatory mechanism:
  • Rok: transcription repression PubMed
  • ResD: transcription activation PubMed
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed