Difference between revisions of "PlsX"
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| − | * '''Description:''' acyl-acyl carrier protein (ACP):phosphate acyltransferase <br/><br/> | + | * '''Description:''' acyl-acyl carrier protein (ACP):phosphate acyltransferase, catalyzes the synthesis of the intermediate fatty acyl-phosphate (acyl-PO4) <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| − | + | ** essential [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed] | |
| − | essential [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed] | + | ** depletion results in sporulation deficiency (via [[SpoIIR]]) {{PubMed|22111992}} |
=== Database entries === | === Database entries === | ||
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=== Additional information=== | === Additional information=== | ||
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' catalyzes the synthesis of the intermediate fatty acyl-phosphate (acyl-PO4) |
* '''Protein family:''' plsX family (according to Swiss-Prot) | * '''Protein family:''' plsX family (according to Swiss-Prot) | ||
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=References= | =References= | ||
| − | + | '''Additional publications:''' {{PubMed|22111992}} | |
<pubmed>12737802, 19282621, 17645809, 17557823, 8759840 16932747 19850612 16091051 21383089</pubmed> | <pubmed>12737802, 19282621, 17645809, 17557823, 8759840 16932747 19850612 16091051 21383089</pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 12:26, 25 November 2011
- Description: acyl-acyl carrier protein (ACP):phosphate acyltransferase, catalyzes the synthesis of the intermediate fatty acyl-phosphate (acyl-PO4)
| Gene name | plsX |
| Synonyms | ylpD |
| Essential | yes PubMed |
| Product | acyl-acyl carrier protein (ACP):phosphate acyltransferase |
| Function | biosynthesis of phospholipids |
| Interactions involving this protein in SubtInteract: PlsX | |
| Metabolic function and regulation of this protein in SubtiPathways: Lipid synthesis | |
| MW, pI | 35 kDa, 5.492 |
| Gene length, protein length | 999 bp, 333 aa |
| Immediate neighbours | fapR, fabD |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
biosynthesis of lipids, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU15890
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: catalyzes the synthesis of the intermediate fatty acyl-phosphate (acyl-PO4)
- Protein family: plsX family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 1VI1
- UniProt: P71018
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Matsumoto lab PubMed
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
