Difference between revisions of "Med"
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| − | * '''Description:''' positive regulator of ''[[comK]]'' <br/><br/> | + | * '''Description:''' lipoprotein, positive regulator of ''[[comK]]'', stimulates [[KinD]]-dependent phosphorylation of [[Spo0A]] <br/><br/> |
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| + | * impaired biofilm formation {{PubMed|21622736}} | ||
| + | |||
=== Database entries === | === Database entries === | ||
| Line 54: | Line 56: | ||
=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
| − | |||
=The protein= | =The protein= | ||
| Line 63: | Line 62: | ||
* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| + | ** stimulates [[KinD]]-dependent phosphorylation of [[Spo0A]] {{PubMed|21622736}} | ||
* '''Protein family:''' BMP lipoprotein family (according to Swiss-Prot) | * '''Protein family:''' BMP lipoprotein family (according to Swiss-Prot) | ||
| Line 129: | Line 129: | ||
=References= | =References= | ||
| − | + | '''Additonal publications:''' {{PubMed|21622736}} | |
<pubmed>9335269,12036071 ,14651647, </pubmed> | <pubmed>9335269,12036071 ,14651647, </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 19:47, 10 June 2011
- Description: lipoprotein, positive regulator of comK, stimulates KinD-dependent phosphorylation of Spo0A
| Gene name | med |
| Synonyms | yjaW |
| Essential | no |
| Product | positive regulator of comK |
| Function | regulation of competence |
| Metabolic function and regulation of this protein in SubtiPathways: Protein secretion | |
| MW, pI | 35 kDa, 4.599 |
| Gene length, protein length | 951 bp, 317 aa |
| Immediate neighbours | yjaV, comZ |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU11300
Phenotypes of a mutant
- impaired biofilm formation PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: BMP lipoprotein family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell surface PubMed
Database entries
- Structure:
- UniProt: O32436
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additonal publications: PubMed
Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647]
[WorldCat.org]
[DOI]
(P p)
Mitsuo Ogura, Hitoshi Hashimoto, Teruo Tanaka
Med, a cell-surface localized protein regulating a competence transcription factor gene, comK, in Bacillus subtilis.
Biosci Biotechnol Biochem: 2002, 66(4);892-6
[PubMed:12036071]
[WorldCat.org]
[DOI]
(P p)
M Ogura, Y Ohshiro, S Hirao, T Tanaka
A new Bacillus subtilis gene, med, encodes a positive regulator of comK.
J Bacteriol: 1997, 179(20);6244-53
[PubMed:9335269]
[WorldCat.org]
[DOI]
(P p)
