Difference between revisions of "ComGE"
| Line 1: | Line 1: | ||
| − | * '''Description:''' DNA transport machinery <br/><br/> | + | * '''Description:''' DNA transport machinery, minor pseudopilin <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || minor pseudopilin |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || competence, DNA uptake | + | |style="background:#ABCDEF;" align="center"|'''Function''' || [[genetic competence]], DNA uptake |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]''' | ||
| Line 54: | Line 54: | ||
=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
| − | |||
=The protein= | =The protein= | ||
| Line 81: | Line 78: | ||
* '''Interactions:''' | * '''Interactions:''' | ||
| + | ** [[ComGB]]-[[ComGE]] {{PubMed|15083159}} | ||
* '''Localization:''' cell surface [http://www.ncbi.nlm.nih.gov/pubmed/9723928 PubMed] | * '''Localization:''' cell surface [http://www.ncbi.nlm.nih.gov/pubmed/9723928 PubMed] | ||
| Line 129: | Line 127: | ||
=References= | =References= | ||
| − | + | ==Reviews== | |
| + | <pubmed> 15083159 </pubmed> | ||
| + | ==Original publications== | ||
<pubmed>9422590,9723928,11814663,2507524,12107147 8196543 </pubmed> | <pubmed>9422590,9723928,11814663,2507524,12107147 8196543 </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 15:05, 8 April 2011
- Description: DNA transport machinery, minor pseudopilin
| Gene name | comGE |
| Synonyms | |
| Essential | no |
| Product | minor pseudopilin |
| Function | genetic competence, DNA uptake |
| Metabolic function and regulation of this protein in SubtiPathways: Protein secretion | |
| MW, pI | 13 kDa, 5.238 |
| Gene length, protein length | 345 bp, 115 aa |
| Immediate neighbours | comGF, comGD |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU24690
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell surface PubMed
Database entries
- Structure:
- UniProt: P25957
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- repressed by casamino acids PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original publications
Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147]
[WorldCat.org]
[DOI]
(P p)
Hanne Jarmer, Randy Berka, Steen Knudsen, Hans H Saxild
Transcriptome analysis documents induced competence of Bacillus subtilis during nitrogen limiting conditions.
FEMS Microbiol Lett: 2002, 206(2);197-200
[PubMed:11814663]
[WorldCat.org]
[DOI]
(P p)
Y S Chung, F Breidt, D Dubnau
Cell surface localization and processing of the ComG proteins, required for DNA binding during transformation of Bacillus subtilis.
Mol Microbiol: 1998, 29(3);905-13
[PubMed:9723928]
[WorldCat.org]
[DOI]
(P p)
Y S Chung, D Dubnau
All seven comG open reading frames are required for DNA binding during transformation of competent Bacillus subtilis.
J Bacteriol: 1998, 180(1);41-5
[PubMed:9422590]
[WorldCat.org]
[DOI]
(P p)
D van Sinderen, A ten Berge, B J Hayema, L Hamoen, G Venema
Molecular cloning and sequence of comK, a gene required for genetic competence in Bacillus subtilis.
Mol Microbiol: 1994, 11(4);695-703
[PubMed:8196543]
[WorldCat.org]
[DOI]
(P p)
M Albano, R Breitling, D A Dubnau
Nucleotide sequence and genetic organization of the Bacillus subtilis comG operon.
J Bacteriol: 1989, 171(10);5386-404
[PubMed:2507524]
[WorldCat.org]
[DOI]
(P p)
