Difference between revisions of "ComGB"
| Line 1: | Line 1: | ||
| − | * '''Description:''' DNA transport machinery <br/><br/> | + | * '''Description:''' polytopic membrane protein , DNA transport machinery <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 12: | Line 12: | ||
|style="background:#ABCDEF;" align="center"| '''Product''' || DNA transport machinery | |style="background:#ABCDEF;" align="center"| '''Product''' || DNA transport machinery | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || competence, DNA uptake | + | |style="background:#ABCDEF;" align="center"|'''Function''' || [[genetic competence]], DNA uptake |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]''' | ||
| Line 34: | Line 34: | ||
= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| − | {{SubtiWiki category|[[genetic competence]]}} | + | {{SubtiWiki category|[[genetic competence]]}}, |
| + | {{SubtiWiki category|[[membrane proteins]]}} | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| Line 54: | Line 55: | ||
=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
| Line 81: | Line 80: | ||
* '''Interactions:''' | * '''Interactions:''' | ||
| + | ** [[ComGA]]-[[ComGB]] {{PubMed|15083159}} | ||
| − | * '''Localization:''' cell | + | * '''Localization:''' cell membrane, polar localization {{PubMed|15083159,12107147}} |
=== Database entries === | === Database entries === | ||
| Line 129: | Line 129: | ||
=References= | =References= | ||
| − | + | ==Reviews== | |
| + | <pubmed> 15083159 </pubmed> | ||
| + | ==Original publications== | ||
<pubmed>9422590,11814663,2507524,12107147,8196543 </pubmed> | <pubmed>9422590,11814663,2507524,12107147,8196543 </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 14:54, 8 April 2011
- Description: polytopic membrane protein , DNA transport machinery
| Gene name | comGB |
| Synonyms | |
| Essential | no |
| Product | DNA transport machinery |
| Function | genetic competence, DNA uptake |
| Metabolic function and regulation of this protein in SubtiPathways: Protein secretion | |
| MW, pI | 36 kDa, 8.654 |
| Gene length, protein length | 969 bp, 323 aa |
| Immediate neighbours | comGC, comGA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
genetic competence, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU24720
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: GSP F family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane, polar localization PubMed
Database entries
- Structure:
- UniProt: P25954
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- repressed by casamino acids PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Inês Chen, David Dubnau
DNA uptake during bacterial transformation.
Nat Rev Microbiol: 2004, 2(3);241-9
[PubMed:15083159]
[WorldCat.org]
[DOI]
(P p)
Original publications
Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147]
[WorldCat.org]
[DOI]
(P p)
Hanne Jarmer, Randy Berka, Steen Knudsen, Hans H Saxild
Transcriptome analysis documents induced competence of Bacillus subtilis during nitrogen limiting conditions.
FEMS Microbiol Lett: 2002, 206(2);197-200
[PubMed:11814663]
[WorldCat.org]
[DOI]
(P p)
Y S Chung, D Dubnau
All seven comG open reading frames are required for DNA binding during transformation of competent Bacillus subtilis.
J Bacteriol: 1998, 180(1);41-5
[PubMed:9422590]
[WorldCat.org]
[DOI]
(P p)
D van Sinderen, A ten Berge, B J Hayema, L Hamoen, G Venema
Molecular cloning and sequence of comK, a gene required for genetic competence in Bacillus subtilis.
Mol Microbiol: 1994, 11(4);695-703
[PubMed:8196543]
[WorldCat.org]
[DOI]
(P p)
M Albano, R Breitling, D A Dubnau
Nucleotide sequence and genetic organization of the Bacillus subtilis comG operon.
J Bacteriol: 1989, 171(10);5386-404
[PubMed:2507524]
[WorldCat.org]
[DOI]
(P p)
