Difference between revisions of "ComS"

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= [[Categories]] containing this gene/protein =
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{{SubtiWiki category|[[genetic competence]]}},
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{{SubtiWiki category|[[short peptides]]}}
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= This gene is a member of the following [[regulons]] =
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{{SubtiWiki regulon|[[CodY regulon]]}},
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{{SubtiWiki regulon|[[ComA regulon]]}},
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{{SubtiWiki regulon|[[PerR regulon]]}},
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{{SubtiWiki regulon|[[Spx regulon]]}}
  
 
=The gene=
 
=The gene=
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= Categories containing this gene/protein =
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{{SubtiWiki category|[[genetic competence]]}},
 
{{SubtiWiki category|[[short peptides]]}}
 
 
=The protein=
 
=The protein=
  

Revision as of 16:39, 8 December 2010

  • Description: antiadaptor protein, assembly link between regulatory components of the competence signal transduction pathway

Gene name comS
Synonyms
Essential no
Product antiadaptor protein (anti-MecA)
Function control of ComK degradation
MW, pI 5 kDa, 9.145
Gene length, protein length 138 bp, 46 aa
Immediate neighbours srfAB, srfAC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ComS context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

genetic competence, short peptides

This gene is a member of the following regulons

CodY regulon, ComA regulon, PerR regulon, Spx regulon

The gene

Basic information

  • Locus tag: BSU03500

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
    • repressed during hydrogen peroxide stress (PerR) PubMed
    • expressed at high cell density (ComA) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Janine Kirstein, Noël Molière, David A Dougan, Kürşad Turgay
Adapting the machine: adaptor proteins for Hsp100/Clp and AAA+ proteases.
Nat Rev Microbiol: 2009, 7(8);589-99
[PubMed:19609260] [WorldCat.org] [DOI] (I p)

Original Publications