Difference between revisions of "YisP"
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| − | * '''Description:''' | + | * '''Description:''' production of squalene-derived polyisoprenoids <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || squalene synthase |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[KinC]] activity |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 7.258 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 7.258 | ||
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===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| − | + | * complete loss of pellicle-forming ability {{PubMed|20713508}} | |
=== Database entries === | === Database entries === | ||
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* '''Modification:''' | * '''Modification:''' | ||
| − | * '''Cofactor(s):''' | + | * '''Cofactor(s):''' NADH {{PubMed|20713508}} |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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=References= | =References= | ||
| − | + | <pubmed> 20713508 19935659</pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:01, 14 October 2010
- Description: production of squalene-derived polyisoprenoids
| Gene name | yisP |
| Synonyms | yucD |
| Essential | no |
| Product | squalene synthase |
| Function | control of KinC activity |
| MW, pI | 31 kDa, 7.258 |
| Gene length, protein length | 822 bp, 274 aa |
| Immediate neighbours | yizA, yisQ |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU10810
Phenotypes of a mutant
- complete loss of pellicle-forming ability PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): NADH PubMed
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O06728
- KEGG entry: [2]
- E.C. number:
Additional information
The gene is annotated in KEGG as an ortholog of phytoene synthase EC 2.5.1.32. No EC annotation is available in Swiss-Prot/MetaCSwiss-Prot/MetaCyc.literature/experimental evidence supporting the annotation is available. PubMed
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Daniel López, Roberto Kolter
Functional microdomains in bacterial membranes.
Genes Dev: 2010, 24(17);1893-902
[PubMed:20713508]
[WorldCat.org]
[DOI]
(I p)
Tzu-Lin Hsiao, Olga Revelles, Lifeng Chen, Uwe Sauer, Dennis Vitkup
Automatic policing of biochemical annotations using genomic correlations.
Nat Chem Biol: 2010, 6(1);34-40
[PubMed:19935659]
[WorldCat.org]
[DOI]
(I p)
