GlcK

• Description: glucose kinase (D-glucose:ATP)
  
  

Gene name	glcK
Synonyms	yqgR
Essential	no
Product	glucose kinase (D-glucose:ATP)
Function	phosphorylation of the free glucose moiety resulting from cleavage of di-and oligosaccharides
Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism, Sugar catabolism
MW, pI	33 kDa, 5.988
Gene length, protein length	963 bp, 321 aa
Immediate neighbours	yqgS, yqgQ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU24850

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + D-glucose = ADP + D-glucose 6-phosphate (according to Swiss-Prot)

• Protein family: ROK (nagC/xylR) family (according to Swiss-Prot)

• Paralogous protein(s): XylR

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure: 2QM1 (from Enterococcus faecalis, 38% identity, 52% similarity)

• UniProt: P54495

• KEGG entry: [2]

• E.C. number: 2.7.1.2

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant: GP2 (spc), available in the Stülke lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: