RbsR

• Description: transcriptional repressor of the ribose operon
  
  

Gene name	rbsR
Synonyms
Essential	no
Product	transcriptional repressor (LacI family)
Function	regulation of ribose utilization
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	35 kDa, 5.577
Gene length, protein length	978 bp, 326 aa
Immediate neighbours	capB, rbsK
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU35910

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: LacI family

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: PtsH-RbsR PubMed

• Localization:

Database entries

• Structure:

• UniProt: P36944

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: rbsR-rbsK-rbsD-rbsA-rbsC-rbsB PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed by glucose (10-fold) (CcpA) PubMed
  • expressed upon transition into the stationary phase (AbrB) PubMed

• Regulatory mechanism:
  • CcpA: transcription repression PubMed
  • AbrB: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: