Difference between revisions of "SpoIIE"

From SubtiWiki
Jump to: navigation, search
(References)
Line 1: Line 1:
* '''Description:''' protein serine phosphatase, septum-associated PP2C, dephosphorylation of [[SpoIIAA]] <br/><br/>
+
* '''Description:''' [[Protein kinases and phosphatases|protein serine phosphatase]], septum-associated PP2C, dephosphorylation of [[SpoIIAA]] <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
Line 10: Line 10:
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || protein serine phosphatase, septum-associated PP2C
+
|style="background:#ABCDEF;" align="center"| '''Product''' || [[Protein kinases and phosphatases|protein serine phosphatase]], septum-associated PP2C
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigF]] activity <br/>required for normal formation of the asymmetric septum
 
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigF]] activity <br/>required for normal formation of the asymmetric septum
Line 56: Line 56:
 
* '''Catalyzed reaction/ biological activity:''' A phosphoprotein + H<sub>2</sub>O = a protein + phosphate (according to Swiss-Prot) dephosphorylation of [[SpoIIAA]]  
 
* '''Catalyzed reaction/ biological activity:''' A phosphoprotein + H<sub>2</sub>O = a protein + phosphate (according to Swiss-Prot) dephosphorylation of [[SpoIIAA]]  
  
* '''Protein family:''' PP2C phosphatase
+
* '''Protein family:''' PP2C [[Protein kinases and phosphatases|phosphatase]]
  
 
* '''Paralogous protein(s):'''
 
* '''Paralogous protein(s):'''

Revision as of 21:06, 19 May 2010

Gene name spoIIE
Synonyms spoIIH, spoIIK
Essential no
Product protein serine phosphatase, septum-associated PP2C
Function control of SigF activity
required for normal formation of the asymmetric septum
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 91 kDa, 6.137
Gene length, protein length 2481 bp, 827 aa
Immediate neighbours trnSL-Glu1, yabS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SpoIIE context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU00640

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: A phosphoprotein + H2O = a protein + phosphate (according to Swiss-Prot) dephosphorylation of SpoIIAA
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon: spoIIE (DBTBS)
  • Regulation:
    • expressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Imrich Barak, Slovak Academy of Science, Bratislava, Slovakia homepage

Your additional remarks

References