Difference between revisions of "PgcA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || interconversion of glucose 6-phosphate and alpha-glucose 1-phosphate
 
|style="background:#ABCDEF;" align="center"|'''Function''' || interconversion of glucose 6-phosphate and alpha-glucose 1-phosphate
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_syn.html Lipid synthesis]'''
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_synthesis.html Lipid synthesis]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 62 kDa, 4.913   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 62 kDa, 4.913   

Revision as of 14:14, 7 March 2010

  • Description: alpha-phosphoglucomutase, required for UDP-glucose synthesis

Gene name pgcA
Synonyms yhxB
Essential no
Product alpha-phosphoglucomutase
Function interconversion of glucose 6-phosphate and alpha-glucose 1-phosphate
Metabolic function and regulation of this protein in SubtiPathways:
Lipid synthesis
MW, pI 62 kDa, 4.913
Gene length, protein length 1695 bp, 565 aa
Immediate neighbours glpD, yhcY
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YhxB context.gif
This image was kindly provided by SubtiList









The gene

Basic information

  • Locus tag: BSU09310

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate (according to Swiss-Prot)
  • Protein family: phosphohexose mutase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylated on ser/ thr/ tyr PubMed, PubMed
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References