Difference between revisions of "AraB"

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(Database entries)
(Expression and regulation)
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=Expression and regulation=
 
=Expression and regulation=
 +
* '''Operon:''' ''[[araA]]-[[araB]]-[[araD]]-[[araL]]-[[araM]]-[[araN]]-[[araP]]-[[araQ]]-[[abfA]]'' {{PubMed|9084180}}
  
* '''Operon:''' ''[[araA]]-[[araB]]-[[araD]]-[[araL]]-[[araM]]-[[araN]]-[[araP]]-[[araQ]]-[[abfA]]''
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|9084180}}
  
* '''[[Sigma factor]]:''' [[sigA]]
+
* '''Regulation:'''
 +
** repressed by glucose ([[CcpA]]) {{PubMed|12949161}}
 +
** induced by arabinose ([[AraR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/10417639 PubMed]
  
* '''Regulation:''' repressed by glucose ([[CcpA]])
+
* '''Regulatory mechanism:'''  
** repressed in the absence of arabinose ([[AraR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/10417639 PubMed]
+
** [[CcpA]]: transcription repression {{PubMed|12949161}}
 
 
* '''Regulatory mechanism:''' [[CcpA]]: transcription repression  
 
 
** [[AraR]]:  transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10417639 PubMed]
 
** [[AraR]]:  transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10417639 PubMed]
  

Revision as of 20:28, 16 December 2009

  • Description: L-ribulokinase

Gene name araB
Synonyms
Essential no
Product L-ribulokinase
Function arabinose utilization
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 60 kDa, 5.233
Gene length, protein length 1680 bp, 560 aa
Immediate neighbours araD, araA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AraB context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU28790

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate (according to Swiss-Prot)
  • Protein family: ribulokinase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 3JVP (B. halodurans AraB)
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References