Difference between revisions of "Spo0B"

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(Phenotypes of a mutant)
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || sporulation initiation phosphotransferase of the [[phosphorelay]]
+
|style="background:#ABCDEF;" align="center"| '''Product''' || sporulation initiation phosphotransferase <br/>
 +
of the [[phosphorelay]]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || initiation of sporulation
 
|style="background:#ABCDEF;" align="center"|'''Function''' || initiation of sporulation
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:''' ''[[spo0B]]-[[obg]]''
+
* '''Operon:''' ''[[spo0B]]-[[obg]]'' {{PubMed|2537815}}
  
* '''[[Sigma factor]]:''' [[SigA]]
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|2537815}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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=References=
 
=References=
  
<pubmed>12730135,2437099,9141138,3918016,9299348,16788205,12067336,9726997,2118512,10997904,1846779,9477965, </pubmed>
+
<pubmed>12730135,2437099,9141138,3918016,9299348,16788205,12067336,9726997,2118512, 10997904,1846779,9477965, 2537815</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 18:54, 13 December 2009

  • Description: sporulation initiation phosphotransferase of the phosphorelay

Gene name spo0B
Synonyms spo0D
Essential no
Product sporulation initiation phosphotransferase

of the phosphorelay

Function initiation of sporulation
MW, pI 22 kDa, 4.963
Gene length, protein length 576 bp, 192 aa
Immediate neighbours obg, rpmA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Spo0B context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU27930

Phenotypes of a mutant

Arrest of sporulation at stage 0 (initiation) PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure: 1F51 (complex with Spo0F), 1IXM
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
    • spo0B12, point mutation 85C>T (=R29W), available in BGSC 1S54
    • spo0B136, amber mutation 103A>T (=K35X), available in BGSC 1S16
    • spo0B580ts, point mutation 193G>A (=E65K), available in BGSC 1S90
    • spo0B581ts, point mutation 461G>A (=G154D), available in BGSC 1S91
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References