Difference between revisions of "IolF"

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(Expression and regulation)
(Expression and regulation)
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=Expression and regulation=
 
=Expression and regulation=
 +
* '''Operon:''' ''[[iolA]]-[[iolB]]-[[iolC]]-[[iolD]]-[[iolE]]-[[iolF]]-[[iolG]]-[[iolH]]-[[iolI]]-[[iolJ]]'' {{PubMed|9226270}}
  
* '''Operon:''' ''[[iolA]]-[[iolB]]-[[iolC]]-[[iolD]]-[[iolE]]-[[iolF]]-[[iolG]]-[[iolH]]-[[iolJ]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/9226270 PubMed]
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|9226270}}
 
 
* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/9226270 PubMed]
 
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
** repressed by glucose ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/10666464 PubMed]
+
** repressed by glucose ([[CcpA]]) {{PubMed|10666464}}
 
** induced by inositol ([[IolR]]) {{PubMed|9887260,9226270}}
 
** induced by inositol ([[IolR]]) {{PubMed|9887260,9226270}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 
** [[IolR]]: transcription repression {{PubMed|9887260,9226270}}
 
** [[IolR]]: transcription repression {{PubMed|9887260,9226270}}
** [[CcpA]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10666464 PubMed]
+
** [[CcpA]]: transcription repression {{PubMed|10666464}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''

Revision as of 22:17, 11 December 2009

  • Description: inositol transport protein

Gene name iolF
Synonyms yxdF
Essential no
Product inositol transport protein
Function myo-inositol uptake
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 47 kDa, 9.474
Gene length, protein length 1317 bp, 439 aa
Immediate neighbours iolG, iolE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
IolF context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU39710

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Ken-ichi Yoshida, Masanori Yamaguchi, Tetsuro Morinaga, Masaki Kinehara, Maya Ikeuchi, Hitoshi Ashida, Yasutaro Fujita
myo-Inositol catabolism in Bacillus subtilis.
J Biol Chem: 2008, 283(16);10415-24
[PubMed:18310071] [WorldCat.org] [DOI] (P p)

Ken-Ichi Yoshida, Yoshiyuki Yamamoto, Kaoru Omae, Mami Yamamoto, Yasutaro Fujita
Identification of two myo-inositol transporter genes of Bacillus subtilis.
J Bacteriol: 2002, 184(4);983-91
[PubMed:11807058] [WorldCat.org] [DOI] (P p)

K I Yoshida, T Shibayama, D Aoyama, Y Fujita
Interaction of a repressor and its binding sites for regulation of the Bacillus subtilis iol divergon.
J Mol Biol: 1999, 285(3);917-29
[PubMed:9887260] [WorldCat.org] [DOI] (P p)

K I Yoshida, D Aoyama, I Ishio, T Shibayama, Y Fujita
Organization and transcription of the myo-inositol operon, iol, of Bacillus subtilis.
J Bacteriol: 1997, 179(14);4591-8
[PubMed:9226270] [WorldCat.org] [DOI] (P p)