Difference between revisions of "CotD"
| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''cotD'' (according to [http://dbtbs.hgc.jp/COG/prom/cotD.html DBTBS]) |
* '''[[Sigma factor]]:''' [[SigK]] {{PubMed|15699190}} | * '''[[Sigma factor]]:''' [[SigK]] {{PubMed|15699190}} | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** | + | ** expressed late during sporulation in the mother cell ([[SigK]], [[SpoIIID]]) {{PubMed|15699190,7966271}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[ | + | ** [[SpoIIID]]: transcription repression {{PubMed|7966271}} |
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 120: | Line 120: | ||
=References= | =References= | ||
| − | <pubmed>,1518043,2821284,2492118,1691789,14651647, </pubmed> | + | <pubmed>,1518043,2821284,2492118,1691789,14651647, 15699190,7966271</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 20:44, 26 October 2009
- Description: spore coat protein (inner)
| Gene name | cotD |
| Synonyms | |
| Essential | no |
| Product | spore coat protein (inner) |
| Function | resistance of the spore |
| MW, pI | 8 kDa, 7.373 |
| Gene length, protein length | 225 bp, 75 aa |
| Immediate neighbours | ypsA, yprB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU22200
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: nhaC Na(+)/H(+) antiporter family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P07791
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: cotD (according to DBTBS)
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647]
[WorldCat.org]
[DOI]
(P p)
R Halberg, L Kroos
Sporulation regulatory protein SpoIIID from Bacillus subtilis activates and represses transcription by both mother-cell-specific forms of RNA polymerase.
J Mol Biol: 1994, 243(3);425-36
[PubMed:7966271]
[WorldCat.org]
[DOI]
(P p)
L Zheng, R Halberg, S Roels, H Ichikawa, L Kroos, R Losick
Sporulation regulatory protein GerE from Bacillus subtilis binds to and can activate or repress transcription from promoters for mother-cell-specific genes.
J Mol Biol: 1992, 226(4);1037-50
[PubMed:1518043]
[WorldCat.org]
[DOI]
(P p)
L B Zheng, R Losick
Cascade regulation of spore coat gene expression in Bacillus subtilis.
J Mol Biol: 1990, 212(4);645-60
[PubMed:1691789]
[WorldCat.org]
[DOI]
(P p)
L Kroos, B Kunkel, R Losick
Switch protein alters specificity of RNA polymerase containing a compartment-specific sigma factor.
Science: 1989, 243(4890);526-9
[PubMed:2492118]
[WorldCat.org]
[DOI]
(P p)
W Donovan, L B Zheng, K Sandman, R Losick
Genes encoding spore coat polypeptides from Bacillus subtilis.
J Mol Biol: 1987, 196(1);1-10
[PubMed:2821284]
[WorldCat.org]
[DOI]
(P p)
