YqgP

• Description: intramembrane protease
  
  

Gene name	yqgP
Synonyms
Essential	no
Product	intramembrane protease
Function	cell division or sugar metabolism
MW, pI	56 kDa, 5.507
Gene length, protein length	1521 bp, 507 aa
Immediate neighbours	yqgQ, yqgO
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU24870

Phenotypes of a mutant

filamentous phenotype PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains (according to Swiss-Prot)

• Protein family: peptidase S54 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: membrane

Database entries

• Structure:

• UniProt: P54493

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Sinisa Urban
Making the cut: central roles of intramembrane proteolysis in pathogenic microorganisms.
Nat Rev Microbiol: 2009, 7(6);411-23
[PubMed:19421188] [WorldCat.org] [DOI] (I p)

Lili R Mesak, Felix M Mesak, Michael K Dahl
Expression of a novel gene, gluP, is essential for normal Bacillus subtilis cell division and contributes to glucose export.
BMC Microbiol: 2004, 4;13
[PubMed:15050034] [WorldCat.org] [DOI] (I e)