Difference between revisions of "BacB"

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|style="background:#ABCDEF;" align="center"| '''Product''' || isomerase component of bacilysin synthetase
 
|style="background:#ABCDEF;" align="center"| '''Product''' || isomerase component of bacilysin synthetase
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || bacilysin production
+
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of the antibiotic bacilysin
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 5.193   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 5.193   
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''[[bacA]]-[[bacB]]-[[bacC]]-[[bacD]]-[[bacE]]-[[bacF]]'' {{PubMed|12372825}}
  
* '''Sigma factor:'''  
+
* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[CodY]]: transcription repression {{PubMed|12372825}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=References=
 
=References=
  
<pubmed>15609023,, </pubmed>
+
<pubmed>15609023,12372825, </pubmed>

Revision as of 21:27, 9 July 2009

  • Description: isomerase component of bacilysin synthetase

Gene name bacB
Synonyms ywfC, ipa-81d
Essential no
Product isomerase component of bacilysin synthetase
Function biosynthesis of the antibiotic bacilysin
MW, pI 26 kDa, 5.193
Gene length, protein length 705 bp, 235 aa
Immediate neighbours bacC, bacA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YwfC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU37730

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Gerhard Steinborn, Mohammad-Reza Hajirezaei, Jürgen Hofemeister
bac genes for recombinant bacilysin and anticapsin production in Bacillus host strains.
Arch Microbiol: 2005, 183(2);71-9
[PubMed:15609023] [WorldCat.org] [DOI] (P p)

Takashi Inaoka, Kosaku Takahashi, Mayumi Ohnishi-Kameyama, Mitsuru Yoshida, Kozo Ochi
Guanine nucleotides guanosine 5'-diphosphate 3'-diphosphate and GTP co-operatively regulate the production of an antibiotic bacilysin in Bacillus subtilis.
J Biol Chem: 2003, 278(4);2169-76
[PubMed:12372825] [WorldCat.org] [DOI] (P p)