spyT

spyT
168

small peptide toxin

locus
BSU_27190
Molecular weight
6.08 kDa
pI
7.02
Protein length
49 aaSequenceBlast
Gene length
150 bpSequenceBlast
function
unknown
product
unknown
essential
no
ec
null
synonyms
yrzI
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms

This gene is a member of the following regulons

Gene
Coordinates
2,778,923 → 2,779,072
The protein
Structure
[AF|O32027]
Expression and Regulation
Operons
genes
[gene|FA18A10769974D392247FB32A0891AE74DF248A0|yrhG]-[gene|C1EC5FB8254E9F8EF5EC02191A533FF9AB9F5D3C|S1027]-[gene|58631F28D723DD51D0BEBF905DA0963F4F16609B|S1026]-[gene|EF487D263F89F53D6A21F9B65B9D3ACAF046D474|spyT]-[gene|9B0ACF91EFB3A032A061AE420696BB357711A187|spyA]-[gene|33145376BA8037C3AD1FFBF5588EF3003AC123C9|S1024]
description
[Pubmed|40055937]
additional information
the mRNA is cleaved by [protein|172652156ABFE72D5BAAC22729CE17CA947538B5|rae1] within the [gene|9B0ACF91EFB3A032A061AE420696BB357711A187|spyA] ORF [pubmed|40055937,28363943]
the mRNA is cleaved by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] upstream of [gene|58631F28D723DD51D0BEBF905DA0963F4F16609B|S1026] and further degraded by [protein|3EB289D0F58A58C693AB588798EE66A731341999|RNase J1]to just upstream of the ribosomal binding site of [gene|EF487D263F89F53D6A21F9B65B9D3ACAF046D474|spyT] [pubmed|40055937]
Open in new tab

[gene|FA18A10769974D392247FB32A0891AE74DF248A0|yrhG]→[gene|33145376BA8037C3AD1FFBF5588EF3003AC123C9|S1024]

2025-04-02 08:27:32

Jstuelk

1

478D15A21D4B6939CD551200581876B18EFA76AA

478D15A21D4B6939CD551200581876B18EFA76AA

genes
[gene|CEA3119463DAA65A18F891479B955235154AE402|yrhF]-[gene|FA18A10769974D392247FB32A0891AE74DF248A0|yrhG]-[gene|C1EC5FB8254E9F8EF5EC02191A533FF9AB9F5D3C|S1027]-[gene|58631F28D723DD51D0BEBF905DA0963F4F16609B|S1026]-[gene|EF487D263F89F53D6A21F9B65B9D3ACAF046D474|spyT]-[gene|9B0ACF91EFB3A032A061AE420696BB357711A187|spyA]-[gene|33145376BA8037C3AD1FFBF5588EF3003AC123C9|S1024]
description
[Pubmed|40055937]
additional information
the mRNA is cleaved by [protein|172652156ABFE72D5BAAC22729CE17CA947538B5|rae1] within the [gene|9B0ACF91EFB3A032A061AE420696BB357711A187|spyA] ORF [pubmed|40055937,28363943]
the mRNA is cleaved by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] upstream of [gene|58631F28D723DD51D0BEBF905DA0963F4F16609B|S1026] and further degraded by [protein|3EB289D0F58A58C693AB588798EE66A731341999|RNase J1]to just upstream of the ribosomal binding site of [gene|EF487D263F89F53D6A21F9B65B9D3ACAF046D474|spyT] [pubmed|40055937]
Open in new tab

[gene|CEA3119463DAA65A18F891479B955235154AE402|yrhF]→[gene|33145376BA8037C3AD1FFBF5588EF3003AC123C9|S1024]

2025-03-31 16:44:24

Jstuelk

0

EC242751708951E42F7F4EFB66114EA10BACAF39

EC242751708951E42F7F4EFB66114EA10BACAF39

genes
[gene|C1EC5FB8254E9F8EF5EC02191A533FF9AB9F5D3C|S1027]-[gene|58631F28D723DD51D0BEBF905DA0963F4F16609B|S1026]-[gene|EF487D263F89F53D6A21F9B65B9D3ACAF046D474|spyT]-[gene|9B0ACF91EFB3A032A061AE420696BB357711A187|spyA]-[gene|33145376BA8037C3AD1FFBF5588EF3003AC123C9|S1024]
description
[Pubmed|40055937,28363943]
expression
expression is increased upon depletion of depletion of tRNA maturation factors [gene|57A79AAF00243B5E058FA901D43AA7B55CA33F63|rnpB] or [gene|C40C5D35ED53D343C8200248FCCB010BAB388054|rnz] [pubmed|36840557]
regulatory mechanism
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: repression, [Pubmed|20817675], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
additional information
the mRNA is cleaved by [protein|172652156ABFE72D5BAAC22729CE17CA947538B5|rae1] within the [gene|9B0ACF91EFB3A032A061AE420696BB357711A187|spyA] ORF [pubmed|40055937,28363943]
the mRNA is cleaved by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] upstream of [gene|58631F28D723DD51D0BEBF905DA0963F4F16609B|S1026] and further degraded by [protein|3EB289D0F58A58C693AB588798EE66A731341999|RNase J1]to just upstream of the ribosomal binding site of [gene|EF487D263F89F53D6A21F9B65B9D3ACAF046D474|spyT] [pubmed|40055937]
Open in new tab

[gene|C1EC5FB8254E9F8EF5EC02191A533FF9AB9F5D3C|S1027]→[gene|33145376BA8037C3AD1FFBF5588EF3003AC123C9|S1024]

2025-03-31 16:43:57

Jstuelk

63

7387FF89B0971DF048D64B7C8F6CE8AFA56DB913

EEBD72C6C3E6BB2E0C578E3361EEE24916BF60BE

Biological materials
Mutant
BKE27190 (Δ[gene|EF487D263F89F53D6A21F9B65B9D3ACAF046D474|spyT]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE27190 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATCGCTCACCCCCTTTC,  downstream forward: _UP4_TAAAAGCAACGAAAAAAACT
BKK27190 (Δ[gene|EF487D263F89F53D6A21F9B65B9D3ACAF046D474|spyT]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK27190 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATATCGCTCACCCCCTTTC,  downstream forward: _UP4_TAAAAGCAACGAAAAAAACT
References
20525796,20817675,28363943,40055937

EF487D263F89F53D6A21F9B65B9D3ACAF046D474

Page visits: 2553

Time of last update: 2025-04-02 18:09:03

Author of last update: Jstuelk