yhaZ
168
similar to alkyl purine DNA glycosylase, probably involved in DNA damage repair
locus
BSU_09810
Molecular weight
41.65 kDa
pI
9.08
function
unknown
product
unknown
essential
no
synonyms
yhaZ, alkC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG4335 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,055,143 1,056,216
The protein
Catalyzed reaction/ biological activity
binds to 8-oxoG, abasic, and RNA base DNA lesions [pubmed|37250769]
Structure
[PDB|5VHV] (from Pseudomonas flourescens, 41% identity) [pubmed|29054852]
[AF|O07541]
Expression and Regulation
Operons
genes
[gene|4873DC24E73F5677AF5C4947B21199904C3EB394|yhaZ]
description
[Pubmed|16267290]
regulation
induced by DNA damage ([protein|search|LexA]) [Pubmed|16267290]
regulatory mechanism
[protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|lexA]: repression, [Pubmed|16267290], in [regulon|protein:D267AF38B0CF107042326E9B8F3DD3C9C85840E4|lexA regulon]
additional information
A [protein|search|ncRNA] is predicted between '[protein|search|yhaZ]' and '[protein|search|yhaX]' [PubMed|20525796]
Biological materials
Mutant
MGNA-A677 (yhaZ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/677 NBRP B. subtilis, Japan]
BKE09810 ([gene|4873DC24E73F5677AF5C4947B21199904C3EB394|yhaZ]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE09810 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATAAACACCGCTTTTTC, downstream forward: _UP4_TGAGTGAATAAAAAATCCCT
BKK09810 ([gene|4873DC24E73F5677AF5C4947B21199904C3EB394|yhaZ]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK09810 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATAAACACCGCTTTTTC, downstream forward: _UP4_TGAGTGAATAAAAAATCCCT
References
Reviews
Original Publications
Page visits: 2008
Time of last update: 2025-04-04 12:25:33
Author of last update: Jstuelk