rtpA
168
anti-TRAP
locus
BSU_02530
Molecular weight
5.51 kDa
pI
4.86
function
regulation of tryptophan biosynthesis
product
anti-TRAP
essential
no
ec
null
synonyms
rtpA, yczA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms
This gene is a member of the following regulons
Gene
Coordinates
277,160 277,321
The protein
[wiki|Cofactors]
Zn2+ [pubmed|37425951]
Structure
[PDB|1N53] (structure of T box RNA), [PDB|2BX9], [PDB|2ZP9] (complex with [protein|E030E80134E9DED6ADBC73C7C7435024CDFD38B9|mtrB])
[AF|O31466]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|354C71C2F6AFE620866D90595E6AC6CEFA5705C3|rtpA]-[gene|EAE919A6088F1A455B6FCE62BA8CCBD05C1F98D5|ycbK]
description
[Pubmed|10706627]
regulation
''[protein|search|rtpA]'': induced by tryptophan limitation ([protein|search|T-box] in the mRNA leader) [Pubmed|10706627]
regulatory mechanism
T-box: RNA switch, [protein|E030E80134E9DED6ADBC73C7C7435024CDFD38B9|mtrB] [pubmed|10706627], in [regulon|other_regulator:T-box|T-box]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|10706627], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
BKE02530 ([gene|354C71C2F6AFE620866D90595E6AC6CEFA5705C3|rtpA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE02530 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGATATCCTCCTTTCT, downstream forward: _UP4_TAAAGGAGAAAAGCTGAGCT
BKK02530 ([gene|354C71C2F6AFE620866D90595E6AC6CEFA5705C3|rtpA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK02530 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGATATCCTCCTTTCT, downstream forward: _UP4_TAAAGGAGAAAAGCTGAGCT
References
Reviews
Original Publications
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Time of last update: 2025-04-03 13:35:29
Author of last update: Jstuelk