csbB
168
lipoteichoic acid glycosyltransferase, generation of C55-P-Glc, general stress protein, required for protection against paraquate stress
locus
BSU_08600
Molecular weight
37.57 kDa
pI
9.2
function
lipoteichoic acid glycosylation , survival of stress conditions
product
lipoteichoic acid glycosyltransferase
synonyms
csbB, yfhN
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0463 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
930,818 931,807
The protein
Protein family
[wiki|glycosyltransferase 2 family] (according to UniProt)
Structure
[PDB|5EKP] (from Synechocystis sp., 44% identity) [pubmed|26729507]
[AF|Q45539]
Paralogous protein(s)
[protein|EF18470AD2B07755431534B52A8FCE6754FDBA9D|ykoT], [protein|FD76A781162795EAF174B59C0A90D2ED3ACC0AB7|ykcC]
[wiki|Localization]
cell membrane (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|824E6AE2FFA3CBC9F90648F15178A00A6CC49E4C|csbB]-[gene|BDFB6CCB5AAD9747971DE6B78E07558706E04617|yfhO]
description
[Pubmed|22383849,8921856]
regulation
induced by stress ([protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]) [Pubmed|8921856,15805528,9636707]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|8921856,9636707], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
[protein|E77364F274A520FCCA9F5C9504E317B047BA29E6|sigX]: sigma factor, [Pubmed|9636707], in [regulon|protein:E77364F274A520FCCA9F5C9504E317B047BA29E6|sigX regulon]
Biological materials
Mutant
MGNA-C319 (csbB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2317 NBRP B. subtilis, Japan]
BKE08600 ([gene|824E6AE2FFA3CBC9F90648F15178A00A6CC49E4C|csbB]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE08600 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTAAGGCACCTTCTTTTT, downstream forward: _UP4_TGAAAATACCAAGCGCCATT
BKK08600 ([gene|824E6AE2FFA3CBC9F90648F15178A00A6CC49E4C|csbB]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK08600 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTAAGGCACCTTCTTTTT, downstream forward: _UP4_TGAAAATACCAAGCGCCATT
References
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Time of last update: 2024-12-21 02:46:00
Author of last update: Jstuelk