prsW
168
protease, cleaves [protein|4E720917045032E8B45CB8AF6E5C13AE0E48EE33|rsiW] in the presence of antimicrobial peptides
locus
BSU_22940
Molecular weight
24.57 kDa
pI
8.09
function
control of [wiki|SigW] activity
product
protease
essential
no
synonyms
prsW, ypdC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2339 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,400,208 → 2,400,864
The protein
Protein family
protease prsW family (single member, according to UniProt)
Structure
[AF|P50738]
[wiki|Localization]
membrane [Pubmed|17020587]
Expression and Regulation
Operons
genes
[gene|EE3B6B52EA19958E2E46A1545747F5209A6AA036|prsW]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-A418 (ypdC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/418 NBRP B. subtilis, Japan]
BKE22940 (Δ[gene|EE3B6B52EA19958E2E46A1545747F5209A6AA036|prsW]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE22940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAGGCAACCTCTTTCCT, downstream forward: _UP4_TAGAAGCCGCACAGCAACCG
BKK22940 (Δ[gene|EE3B6B52EA19958E2E46A1545747F5209A6AA036|prsW]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK22940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAGGCAACCTCTTTCCT, downstream forward: _UP4_TAGAAGCCGCACAGCAACCG
labs
[wiki|Thomas Wiegert], University of Bayreuth, Germany [http://www.genetik.uni-bayreuth.de/LSGenetik1/Thomas%20Wiegert-Dateien/Thomas%20Wiegert.html Homepage]
References
Reviews
Original Publications
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Time of last update: 2025-04-04 16:41:13
Author of last update: Jstuelk