yobH
168
C-terminal fragment of the Y family DNA polymerase [protein|A04F698C8836E84991BC875BCB7B1460D8E74A8E|yozK]-[protein|ED0A85A8A5FCD12C99507EB033F88586521A7C47|yobH]
locus
BSU_18930
Molecular weight
23.06 kDa
pI
10
function
unknown
product
unknown
essential
no
synonyms
yobH
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms
This gene is a member of the following regulons
Gene
Phenotypes of a mutant
reduced formation of [gene|F1969E4C7BAAF70BCBE570F58350C12A3E417539|rpsB] or [gene|144D952B05EBBFF41EC92DF906543EA00475FE69|rpsE] suppressor mutants after mitomycin treatment [pubmed|34339280]
The protein
Protein family
[wiki|DNA polymerase type-Y family] (according to UniProt)
[wiki|Domains]
[wiki|UmuC domain] (aa 1-68) (according to UniProt)
Structure
[PDB|4DEZ] (from Mycobacterium smegmatis, 24% identity) [pubmed|22868761]
[AF|C0SPA8]
Expression and Regulation
Operons
genes
[gene|94F2146AC6998CC77CD2E86CE8BE8DC98AEBB9CD|yozL]-[gene|A04F698C8836E84991BC875BCB7B1460D8E74A8E|yozK]-[gene|ED0A85A8A5FCD12C99507EB033F88586521A7C47|yobH]
description
[Pubmed|16267290]
regulation
expression during spore [wiki|germination] is strongly reduced under conditions of osmotic stress [Pubmed|27766092]
regulatory mechanism
[protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|lexA]: repression, [Pubmed|16267290], in [regulon|protein:D267AF38B0CF107042326E9B8F3DD3C9C85840E4|lexA regulon]
Biological materials
Mutant
MGNA-A306 (yobH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/306 NBRP B. subtilis, Japan]
BKE18930 (Δ[gene|ED0A85A8A5FCD12C99507EB033F88586521A7C47|yobH]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE18930 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCTTCAGGATTCTCTT, downstream forward: _UP4_TGAGAAGTATCTCAGTTACG
BKK18930 (Δ[gene|ED0A85A8A5FCD12C99507EB033F88586521A7C47|yobH]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK18930 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCTTCAGGATTCTCTT, downstream forward: _UP4_TGAGAAGTATCTCAGTTACG
References
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Time of last update: 2025-04-04 20:45:28
Author of last update: Jstuelk