yhxA
168
similar to adenosylmethionine-8-amino-7-oxononanoate aminotransferase
locus
BSU_09260
Molecular weight
49.71 kDa
pI
5.64
function
unknown
product
unknown
essential
no
synonyms
yhxA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0161 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,000,364 → 1,001,716
The protein
Protein family
[wiki|Class-III pyridoxal-phosphate-dependent aminotransferase family] (according to UniProt)
[wiki|Cofactors]
PLP (according to UniProt)
Structure
[PDB|3N5M] (from ''Bacillus Anthracis'', 64% identity)
[AF|P33189]
Paralogous protein(s)
[protein|7FA5502FE82D55EC176F68B74B24293EC9B7D4D7|argD], [protein|617FE9E40E8822D58B0446128585CB6CA05A50C6|rocD]
[protein|13DC4296015A28975BC7697F134FB6ECD6B11489|yodT], (34,9%)
[protein|68C86FED3575B864C576DFB73FE7B5BF83994D1F|bioA], (33,6%)
[protein|4E1FD02C6FE4103E3B4942BF5221C062CB8D0B9B|gabT], (32.8%)
Additional information
subject to Clp-dependent proteolysis upon glucose starvation [Pubmed|17981983]
Expression and Regulation
Operons
genes
[gene|E5F6DF14A4C01B2C90F70E37908D3697BC1B5FEF|yhxA]-[gene|38767691AE7E09F46B9E97A60BF5358C1876EDF8|glpP]
description
[Pubmed|2127799]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|21925382], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
additional information
half-life of the mRNA: 3.7 min [PubMed|21925382]
half-life of the mRNA: 3.7 min [PubMed|21925382]
Biological materials
Mutant
MGNA-B475 (yhxA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1474 NBRP B. subtilis, Japan]
BKE09260 (Δ[gene|E5F6DF14A4C01B2C90F70E37908D3697BC1B5FEF|yhxA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE09260 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCATTAGCGTTCCCTA, downstream forward: _UP4_TAATATAAAAGTGAATTATT
BKK09260 (Δ[gene|E5F6DF14A4C01B2C90F70E37908D3697BC1B5FEF|yhxA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK09260 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCATTAGCGTTCCCTA, downstream forward: _UP4_TAATATAAAAGTGAATTATT
References
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Time of last update: 2025-01-20 14:53:54
Author of last update: Jstuelk