acoA
168
acetoin dehydrogenase E1 component (TPP-dependent alpha subunit)
Locus
BSU_08060
Molecular weight
35.91 kDa
Isoelectric point
4.91
Function
acetoin utilization
Product
acetoin dehydrogenase E1 component (TPP-dependent alpha subunit)
Essential
no
Synonyms
acoA, yfjK
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1071 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
879,002 → 880,003
The protein
TPP PubMed
Structure
6CFO (PDB) (human PDH, E1, 38% identity) PubMed
Paralogous protein(s)
cytoplasm (homogeneous) PubMed
Expression and Regulation
Operons
Description
Regulation
Regulatory mechanism
AcoR: activation, (interaction with SigL-containing RNA polymerase) [ PubMed|11274109], in acoR regulon
Fnr: indirect positive regulation, in fnr regulon
Sigma factors
Additional information
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Additional information
the mRNA is very stable (> 15 min) PubMed
Biological materials
Mutant
MGNA-C280 (acoA::erm), available at the NBRP B. subtilis, Japan
References
Reviews
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Original Publications
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Time of last update: 2025-03-16 18:00:18
Author of last update: Jstuelk