mneS
168
secondary manganese (II) efflux pump, contributes to iron efflux
Locus
BSU_06320
Molecular weight
31.63 kDa
Isoelectric point
5.63
Function
Mn(II) export
Product
manganese (II) efflux pump
Essential
no
Synonyms
mneS, undefined, ydxT, yeaB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0053 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
686,962 687,834
Phenotypes of a mutant
a mneP mneS double mutant is extremely senitive to Mn2+ intoxication, this results in generation of reactive radicals by poisoned cytochrome aa3 oxidase QoxA-QoxB-QoxC-QoxD and can be suppressed by inactivation of QoxA-QoxB-QoxC-QoxD (any gene) or of mhqR to activate the electrophile stress response PubMed
The protein
Catalyzed reaction/ biological activity
Protein family
Structure
5VRF (PDB) (from Shewanella oneidensis, 28% identity) PubMed
Paralogous protein(s)
cell membrane (according to UniProt)
Expression and Regulation
Operons
Biological materials
Mutant
MGNA-A914 (yeaB::erm), available at the NBRP B. subtilis, Japan
References
Reviews
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Original Publications
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Time of last update: 2025-06-02 21:09:32
Author of last update: Jstuelk