ytkP
168
similar to cysteine synthase
locus
BSU_29970
Molecular weight
32.91 kDa
pI
4.93
function
unknown
product
unknown
essential
no
ec
2.5.1.47
synonyms
ytkP
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0031 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,066,451 → 3,067,386
The protein
Catalyzed reaction/ biological activity
O(3)-acetyl-L-serine + H2S --> L-cysteine + acetate (according to UniProt)
Protein family
Cysteine synthase/cystathionine beta-synthase family (with [protein|D1FC976597E5583E40A4ED7234FBCA743AB01354|cysK] and [protein|F195C47849F4F6B4C56E3A386F5D8C84326B01C4|mccA], according to UniProt)
[wiki|Cofactors]
PLP (according to UniProt)
Structure
[PDB|2EGU] (from Geobacillus Kaustophilus 57% identity)
[AF|O34476]
Paralogous protein(s)
[protein|D1FC976597E5583E40A4ED7234FBCA743AB01354|cysK], [protein|F195C47849F4F6B4C56E3A386F5D8C84326B01C4|mccA]
[wiki|Localization]
cytoplasm (according to UniProt)
Expression and Regulation
Operons
genes
[gene|6F1462EA074DEDE2FEF13561A6691A22BFAD10FE|ytkP]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-B534 (ytkP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1533 NBRP B. subtilis, Japan]
BKE29970 (Δ[gene|6F1462EA074DEDE2FEF13561A6691A22BFAD10FE|ytkP]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE29970 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGTCATTCCTTTCTGAA, downstream forward: _UP4_TAAAAAAAGGACTGGCTTCA
BKK29970 (Δ[gene|6F1462EA074DEDE2FEF13561A6691A22BFAD10FE|ytkP]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK29970 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGTCATTCCTTTCTGAA, downstream forward: _UP4_TAAAAAAAGGACTGGCTTCA
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Time of last update: 2025-04-03 07:30:58
Author of last update: Melvin.boenninger