yusI
168
similar to arsenate reductase, binds to DNA lesions, may be involved in DNA repair
locus
BSU_32810
Molecular weight
13.77 kDa
pI
5.59
function
unknown
product
unknown
essential
no
synonyms
yusI
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1393 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,366,573 3,366,929
The protein
Catalyzed reaction/ biological activity
binds to RNA base DNA lesions [pubmed|37250769]
Protein family
ArsC family (with [protein|6A38DAA96F7BBF31FD8A4018A8CA7A72F3C28F79|mgsR] and [protein|2C6386E9A63F410558D168798D077DF91590F454|spx], according to UniProt)
Structure
[PDB|2M46] (from Staphylococcus aureus, 51% identity)
[AF|O32175]
Expression and Regulation
Operons
genes
[gene|5278DD377B110CC14E239B9428F1985B472EEDF5|yusI]-[gene|58CF62EBA28E77668A0B5319142C8AC20D81CD8A|gcvH]-[gene|0253D9B030630340551DC2D4F40B3B118DB0EC56|yusG]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-B593 (yusI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1592 NBRP B. subtilis, Japan]
BKE32810 ([gene|5278DD377B110CC14E239B9428F1985B472EEDF5|yusI]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE32810 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTTCTTCCCCCTCAATA, downstream forward: _UP4_TAATGTAAATTTTTTTTGAA
BKK32810 ([gene|5278DD377B110CC14E239B9428F1985B472EEDF5|yusI]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK32810 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTTCTTCCCCCTCAATA, downstream forward: _UP4_TAATGTAAATTTTTTTTGAA
Original Publications
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Time of last update: 2025-04-11 19:43:00
Author of last update: Jstuelk