glnL

glnL
168

two-component response regulator, regulation of the glsA-glnT operon

Locus
BSU_02450
Molecular weight
35.56 kDa
Isoelectric point
7.02
Protein length
314 aaSequenceBlast
Gene length
945 bpSequenceBlast
Function
regulation of the glsA-glnT operon
Product
two-component response regulator
Essential
no
E.C.
null
Synonyms
glnL, ycbB, yzgB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2197 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
266,719  267,663
The protein
Domains
Response regulatory domain (aa 2–118) (according to UniProt)
Structure
P40759 (AlphaFold)
Modification
phosphorylated by GlnK on an Asp residue
Effectors of protein activity
phosphorylation likely affects DNA-binding activity
Localization
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
glnK-glnL
Description
PubMed
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glnK→glnL

2025-04-10 00:08:07

Jstuelk

89

53ffb3f99cce8c4721a7de587eae3ce84afee383

5FB071BA0D146528DE35BFF31F938BD208BF8C20

Biological materials
Mutant
MGNA-C026 (ycbB::erm), available at the NBRP B. subtilis, Japan
BKE02450 (glnL::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAGCTTTTGGTTCACCCT,  downstream forward: _UP4_TAAACCAAACAGCCGGCTGA
BKK02450 (glnL::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAGCTTTTGGTTCACCCT,  downstream forward: _UP4_TAAACCAAACAGCCGGCTGA
References
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4E6EA2EABBDAA427E8F9EE1AE1800AF8657CF18B

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Time of last update: 2025-04-11 06:01:22

Author of last update: Melvin.boenninger