recS
168
ATP-dependent DNA helicase
locus
BSU_23020
Molecular weight
56.34 kDa
pI
6.23
function
replication reactivation pathway
product
ATP-dependent DNA helicase
essential
no
synonyms
recS, recS, ypbC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0514 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,406,922 2,408,412
The protein
Catalyzed reaction/ biological activity
ATP + H2O --> ADP + H+ + phosphate (according to UniProt)
Protein family
[wiki|helicase family] (according to UniProt)
[wiki|Domains]
[wiki|Helicase ATP-binding domain] (aa 25-192) (according to UniProt)
[wiki|Helicase C-terminal domain] (aa 219-363) (according to UniProt)
Structure
[PDB|4Q47] ([protein|E6EA8098E37A4A2F7370920AC1A500EE4319AAA2|recQ] from Deinococcus radiodurans, corresponds to aa 8 ... 394, 38% identity) [pubmed|25243132]
[AF|P50729]
Paralogous protein(s)
[protein|E6EA8098E37A4A2F7370920AC1A500EE4319AAA2|recQ]
[wiki|Localization]
cytoplasm (according to UniProt)
Biological materials
Mutant
GP3531 (Δ[gene|4A4FCD876C3CA1D821792803CA2A0CB2E97D3F5E|recS]::kan), available in [wiki|Jörg Stülke]'s lab
1A893 (no resistance), [Pubmed|16020779], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A893&Search=1A893 BGSC]
BKE23020 ([gene|4A4FCD876C3CA1D821792803CA2A0CB2E97D3F5E|recS]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE23020 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AAACTGATATAACGTTTGCT, downstream forward: _UP4_TGAAACAGCAAAAAGATTAT
BKK23020 ([gene|4A4FCD876C3CA1D821792803CA2A0CB2E97D3F5E|recS]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK23020 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AAACTGATATAACGTTTGCT, downstream forward: _UP4_TGAAACAGCAAAAAGATTAT
References
Reviews
Original Publications
Page visits: 961
Time of last update: 2025-03-16 05:49:45
Author of last update: MBenda