[gene|651C370386E9FB45E3B98001800D342FEDB43E9A|ribU]
genes
[gene|651C370386E9FB45E3B98001800D342FEDB43E9A|ribU]
description
[Pubmed|21815947]
regulation
expressed in the absence of FMN ([protein|search|FMN-box]) [Pubmed|17693491]
antitermination is modulated by [protein|43CFA3477B4EEB4CE0B2DF63ED2B5EDB171E79C7|nusG]-dependent transcription pausing just upstream of the [protein|search|FMN-box] [pubmed|39494516]
binding of [protein|3D32B6C1DC9CAC615B02E14EA846648C3B0E61D6|ribR] to the [wiki|FMN-box] riboswitch can enforce expression even in the presence of FMN [pubmed|26494285]
regulatory mechanism
FMN-box: RNA switch, via [protein|C245476CE35028167510F67153F392D91447553F|mgtE riboswitch], sequestration of the Shine-Dalgarno sequence in the presence of FMN or FMNH2, this is counter-acted upon binding of [protein|3D32B6C1DC9CAC615B02E14EA846648C3B0E61D6|ribR], in [regulon|other_regulator:FMN-box|FMN-box]
[protein|3D32B6C1DC9CAC615B02E14EA846648C3B0E61D6|ribR]: antitermination, [pubmed|26494285], in [regulon|protein:3D32B6C1DC9CAC615B02E14EA846648C3B0E61D6|ribR regulon]
additional information
the mRNA is substantially stabilized upon depletion of [gene|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] [PubMed|21815947]
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Time of last update: 2024-11-16 02:53:21
Author of last update: Jstuelk