comQ

comQ
168

prenylation of [protein|search|comX ]and surfactin expression ([gene|search|srfA])

locus
BSU_31710
Molecular weight
34.05 kDa
pI
4.89
Protein length
299 aaSequenceBlast
Gene length
900 bpSequenceBlast
function
regulation of quorum sensing
product
prenyltransferase
essential
no
synonyms
comQ
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0142 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,256,008 → 3,256,907
Phenotypes of a mutant
the mutation suppresses the mucoid phenotype of ''[gene|86C729C7D5ABEE519ADC4A893940600BBB655EF1|motA]'' or ''[gene|FE56753D061344B0F10A6523F49C5C7356AA40B6|motB]'' mutants due to loss of [protein|D343D2096664A972026D911E7A17A35C7B1CD1C9|degU] phosphorylation and concomitant reduced expression of the ''[gene|86C05126ADBA22BB1771B1FA3D214B2E7A36311E|capB]-[gene|D66994D077D1382B88FF65075E44C2A31089548F|capC]-[gene|A696434A086A428D411CAF45B37CD8F82AC2503F|capA]-[gene|6B61DCE8D27776EBF942621D3AE90F410FD13F37|capE]'' operon [Pubmed|24296669]
The protein
Catalyzed reaction/ biological activity
prenylation of [protein|60D6EB02923D9ADE88F61A8CBBD882BA8BDD457E|comX] on W-53 [Pubmed|22878193]
Structure
[AF|P33690]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|FDACEF9DDC3BEA4EB013AE67BC47ADA532F00205|comQ]-[gene|60D6EB02923D9ADE88F61A8CBBD882BA8BDD457E|comX]-[gene|5A00E233F0B5A0DAB18D2ECC55527F1911987F86|comP]-[gene|7832489F11F606BCF637EC23BAAB41AD10237EBB|comA]-[gene|015989AAB862E418C944AB35DA3605863F059CE9|yuxO]
description
[Pubmed|22383849]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|2507523], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
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[gene|FDACEF9DDC3BEA4EB013AE67BC47ADA532F00205|comQ]→[gene|015989AAB862E418C944AB35DA3605863F059CE9|yuxO]

2024-11-30 06:57:07

Jstuelk

98

150fea5ac7a55e0a32a0fafb306d0c860c9a2be7

E73017881E40042997BB444071E259402A0F5D1F

Biological materials
Mutant
BKE31710 (Δ[gene|FDACEF9DDC3BEA4EB013AE67BC47ADA532F00205|comQ]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE31710 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTTCTCCTTGATCCGGA,  downstream forward: _UP4_AGTTATACAAAGGGGGATAC
BKK31710 (Δ[gene|FDACEF9DDC3BEA4EB013AE67BC47ADA532F00205|comQ]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK31710 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTTCTCCTTGATCCGGA,  downstream forward: _UP4_AGTTATACAAAGGGGGATAC
References
Reviews
28326143,30218468
Original Publications
12067344,25666134,19605685,22878193,11133937,1715859,19114482,24296669,24425772,24788106,25036949,25757097,26787913,29038467,31670609,37527273,37676037

FDACEF9DDC3BEA4EB013AE67BC47ADA532F00205

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Time of last update: 2024-12-20 12:27:06

Author of last update: Jstuelk