ykcC
168
lipoteichoic acid glycosyltransferase, generation of C55-P-Glc
locus
BSU_12890
Molecular weight
37.22 kDa
pI
8.01
function
glycosylation of teichoic acids
product
glycosyltransferase
essential
no
synonyms
ykcC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0463 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,356,447 → 1,357,418
The protein
Protein family
[wiki|glycosyltransferase 2 family] (according to UniProt)
Structure
[PDB|5EKP] (from Synechocystis sp., 47% identity) [pubmed|26729507]
[AF|O34319]
Paralogous protein(s)
[protein|824E6AE2FFA3CBC9F90648F15178A00A6CC49E4C|csbB]
[protein|EF18470AD2B07755431534B52A8FCE6754FDBA9D|ykoT], (39%)
[wiki|Localization]
cell membrane (heterogeneous) [Pubmed|16479537]
Expression and Regulation
Operons
genes
[gene|7039FCF49F97FFEF37ED48D6F860E3873A5CF308|ykcB]-[gene|FD76A781162795EAF174B59C0A90D2ED3ACC0AB7|ykcC]
description
[Pubmed|18175906]
regulatory mechanism
[protein|706983E6942E883D3A9D45693E7B4015AEABE60B|yclJ]: activation, [Pubmed|20512483], in [regulon|protein:706983E6942E883D3A9D45693E7B4015AEABE60B|yclJ regulon]
[protein|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|yrkP]: activation, [Pubmed|18175906], in [regulon|protein:1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|yrkP regulon]
Biological materials
Mutant
MGNA-A739 (ykcC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/739 NBRP B. subtilis, Japan]
BKE12890 (Δ[gene|FD76A781162795EAF174B59C0A90D2ED3ACC0AB7|ykcC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE12890 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATGTCTGCTCATGTTTTTGC, downstream forward: _UP4_TAACCTCAAACCCCCTGTCC
BKK12890 (Δ[gene|FD76A781162795EAF174B59C0A90D2ED3ACC0AB7|ykcC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK12890 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATGTCTGCTCATGTTTTTGC, downstream forward: _UP4_TAACCTCAAACCCCCTGTCC
References
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Time of last update: 2024-12-22 08:14:39
Author of last update: Jstuelk