nrdEB
168
similar to ribonucleoside-diphosphate reductase (alpha subunit)
locus
BSU_20060
Molecular weight
27.82 kDa
pI
6.39
function
unknown
product
unknown
essential
no
synonyms
nrdEB, yosN
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1372 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,162,108 → 2,165,614
The protein
Catalyzed reaction/ biological activity
[thioredoxin]-disulfide + 2'-deoxyribonucleoside 5'-diphosphate + H2O --> [thioredoxin]-dithiol + ribonucleoside 5'-diphosphate (according to UniProt)
Protein family
ribonucleoside diphosphate reductase large chain family (with [protein|3B68CE8E9A35997B45E437A316996D585E43B76B|nrdE], according to UniProt)
[wiki|Domains]
DOD-type homing endonuclease domain (aa 503-654) (according to UniProt)
Structure
[AF|O31875]
Paralogous protein(s)
[protein|3B68CE8E9A35997B45E437A316996D585E43B76B|nrdE]
Biological materials
Mutant
BKE20060 (Δ[gene|FD4CD7DB35AA20DBBEC0A4DA5D88282D89CCDA6D|nrdEB]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE20060 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTATTGAGCTTGATCCAA, downstream forward: _UP4_TAATAGGTACGTTTACGTTT
BKK20060 (Δ[gene|FD4CD7DB35AA20DBBEC0A4DA5D88282D89CCDA6D|nrdEB]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK20060 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTATTGAGCTTGATCCAA, downstream forward: _UP4_TAATAGGTACGTTTACGTTT
References
Page visits: 3748
Time of last update: 2024-10-14 07:51:25
Author of last update: Melvin.boenninger