yknX
168
ABC-type antimicrobial peptide transporter (permease) for the export of the [protein|820635420B3980B620F3E3D7ACF7EDE9DC6275AD|sdpC] toxin
locus
BSU_14350
Molecular weight
41.55 kDa
pI
5.18
function
resistence against [protein|820635420B3980B620F3E3D7ACF7EDE9DC6275AD|sdpC] toxin
product
ABC-type antimicrobial peptide exporter (permease)
essential
no
synonyms
yknX
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0845 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,504,282 → 1,505,415
The protein
Protein family
[wiki|Membrane fusion protein (MFP) (TC 8.A.1) family] (according to UniProt)
Structure
[PDB|4DK0] (from Actinobacillus actinomycetemcomitans, 24% identity) [pubmed|22308040]
[AF|O31710]
[wiki|Localization]
membrane protein with a large extracytoplasmic domain [Pubmed|22707703]
Expression and Regulation
Operons
genes
[gene|70D7098BEBD5E53B4B9B8C3394FAAF972C65EE22|yknU]-[gene|C6B0ACB9D9703DD8141FD7D9D62DB22FB48F458B|yknV]-[gene|916419C4ED113778488EBC558A35810498028B02|yknW]-[gene|FD270195901B89DAAAD134DB9DE729670A9BDECF|yknX]-[gene|FE3A01BEA974C5E32C68DC600C800E5EF101B34F|yknY]-[gene|9680326BAA94A503E2A5C6F0A2479AE0B0467B4C|yknZ]
description
[Pubmed|22383849]
genes
[gene|916419C4ED113778488EBC558A35810498028B02|yknW]-[gene|FD270195901B89DAAAD134DB9DE729670A9BDECF|yknX]-[gene|FE3A01BEA974C5E32C68DC600C800E5EF101B34F|yknY]-[gene|9680326BAA94A503E2A5C6F0A2479AE0B0467B4C|yknZ]
description
[Pubmed|9987136]
regulation
repressed during logrithmic growth ([protein|search|AbrB]) [Pubmed|12076816]
regulatory mechanism
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: repression, [Pubmed|12076816], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
sigma factors
[protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|sigW]: sigma factor, [Pubmed|9987136], in [regulon|protein:3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|sigW regulon]
Biological materials
Mutant
MGNA-B349 (yknX::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1348 NBRP B. subtilis, Japan]
BKE14350 (Δ[gene|FD270195901B89DAAAD134DB9DE729670A9BDECF|yknX]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE14350 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TCCGATCCAGACTTTTTTCA, downstream forward: _UP4_GACGGAATGGAAGTGAAATC
BKK14350 (Δ[gene|FD270195901B89DAAAD134DB9DE729670A9BDECF|yknX]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK14350 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TCCGATCCAGACTTTTTTCA, downstream forward: _UP4_GACGGAATGGAAGTGAAATC
References
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Time of last update: 2024-12-21 00:09:59
Author of last update: Jstuelk