bsdC
168
phenolic acid decarboxylase
locus
BSU_03640
Molecular weight
52.86 kDa
pI
5.12
function
resistance to salicylic acid
product
phenolic acid decarboxylase
essential
no
synonyms
bsdC, yclC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0043 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
413,157 → 414,578
The protein
Catalyzed reaction/ biological activity
conversion of vanillic acid to guaiacol [Pubmed|26658822]
4-hydroxybenzoate + H+ --> CO2 + phenol (according to UniProt)
4-hydroxy-3-methoxybenzoate + H+ --> CO2 + guaiacol (according to UniProt)
Protein family
ubiD family (single memberm, according to UniProt)
Structure
[PDB|5M1B] (from E. coli, 31% identity) [pubmed|28057757]
[AF|P94405]
Expression and Regulation
Operons
genes
[gene|8A83E44AFE9A1A635C65E6B526690AF7DA201BE1|bsdB]-[gene|FD23F4C2AFCBFE35A79116C5A707FACD454E4180|bsdC]-[gene|868DC9DE1C9C26C780F4CEAA4185640B5B6B781B|bsdD]
description
[Pubmed|17295427]
regulation
induced by salicylic acid ([protein|search|BsdA]) [Pubmed|17295427]
regulatory mechanism
[protein|28D03575FA24525C162E6C161631034568E89622|bsdA]: activation, [Pubmed|17295427], in [regulon|protein:28D03575FA24525C162E6C161631034568E89622|bsdA regulon]
Biological materials
Mutant
MGNA-C062 (yclC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2060 NBRP B. subtilis, Japan]
BKE03640 (Δ[gene|FD23F4C2AFCBFE35A79116C5A707FACD454E4180|bsdC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE03640 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TCTGAAATCTTGATAAGCCA, downstream forward: _UP4_AATAAATAAGGAAAGGATGT
BKK03640 (Δ[gene|FD23F4C2AFCBFE35A79116C5A707FACD454E4180|bsdC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK03640 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TCTGAAATCTTGATAAGCCA, downstream forward: _UP4_AATAAATAAGGAAAGGATGT
References
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Time of last update: 2025-04-01 22:01:06
Author of last update: Melvin.boenninger