ytdA

ytdA
168

similar to UTP-glucose-1-phosphate uridylyltransferase

locus
BSU_30850
Molecular weight
30.03 kDa
pI
5.91
Protein length
Gene length
function
unknown
product
unknown
essential
no
ec
2.7.7.9
synonyms
ytdA, yzwA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1210 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,154,735 → 3,155,553
The protein
Catalyzed reaction/ biological activity
α-D-glucose 1-phosphate + H+ + UTP --> diphosphate + UDP-α-D-glucose (according to UniProt)
Protein family
UDPGP type 2 family (with [protein|D368988F85D8436DD424B0B4A1591BDF092A8EA7|gtaB] and [protein|69C5D9EF7ED43BCAB7A9D6148EDD323CE72F8E3D|yngB], according to UniProt)
Structure
[PDB|7B1R] ([protein|69C5D9EF7ED43BCAB7A9D6148EDD323CE72F8E3D|yngB], 44% identity) [pubmed|33556370]
[PDB|3JUJ] (UDP-glucose pyrophosphorylase from ''Helicobacter pylori'', 43% identity) [Pubmed|20238176]
[AF|P42407]
Paralogous protein(s)
[protein|69C5D9EF7ED43BCAB7A9D6148EDD323CE72F8E3D|yngB], [protein|D368988F85D8436DD424B0B4A1591BDF092A8EA7|gtaB]
[wiki|Localization]
outer spore coat [Pubmed|26577401]
Expression and Regulation
Operons
genes
[gene|FC455B727F66632D94D93E103B30748944ED04A0|ytdA]
description
[Pubmed|22383849]
regulation
expressed late during [wiki|sporulation] in the mother cell ([wiki|SigK]) [Pubmed|26577401]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
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[gene|FC455B727F66632D94D93E103B30748944ED04A0|ytdA]

2024-10-11 07:30:37

ghost

45

8b3abb6216088005e03bebf15704e9cb470f7380

104CB5E82C9E81B20F659DA196EA459534C721EC

Biological materials
Mutant
MGNA-A281 (ytdA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/281 NBRP B. subtilis, Japan]
BKE30850 (Δ[gene|FC455B727F66632D94D93E103B30748944ED04A0|ytdA]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE30850 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGGTATTTTCCCCTCAGC,  downstream forward: _UP4_AAGAACCCCCAATAATTGGG
BKK30850 (Δ[gene|FC455B727F66632D94D93E103B30748944ED04A0|ytdA]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK30850 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGGTATTTTCCCCTCAGC,  downstream forward: _UP4_AAGAACCCCCAATAATTGGG
References
26577401,20238176,22383849,33556370,35638784

FC455B727F66632D94D93E103B30748944ED04A0

Page visits: 4559

Time of last update: 2024-10-11 19:15:33

Author of last update: Jstuelk