cotD
168
spore coat protein (inner)
locus
BSU_22200
Molecular weight
8.70 kDa
pI
7.37
function
resistance of the spore
product
spore coat protein (inner)
essential
no
ec
null
synonyms
cotD
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG5879 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,332,784 → 2,333,011
The protein
Structure
[AF|P07791]
[wiki|Localization]
inner spore coat [Pubmed|19933362], localization depends on [protein|CEBEC9CECCF445C40D793E61A2CD23175631A473|safA] [Pubmed|22171814]
Expression and Regulation
Operons
genes
[gene|FA8D9AA0968365522DEFC05B277123FC96482044|cotD]
description
[Pubmed|22383849]
regulation
expressed late during sporulation in the mother cell ([protein|search|SigK], [wiki|SpoIIID], [protein|search|GerE]) [Pubmed|15383836,15699190,7966271]
regulatory mechanism
[protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID]: repression, [Pubmed|7966271], in [regulon|protein:90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID regulon]
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]: activation, [Pubmed|15383836], in [regulon|protein:19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE regulon]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|15699190], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
genes
[gene|4D286C045A43FBF0F6E93E9E46AD7F25E35ADA7C|mrfA]-[gene|3F1D78CAAA4B5057DEBB24C4D382F96DA4AA4852|mrfB]-[gene|FA8D9AA0968365522DEFC05B277123FC96482044|cotD]
description
[Pubmed|22383849]
Biological materials
Mutant
1S104 ( ''cotD''::''cat''), [Pubmed|2821284], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S104&Search=1S104 BGSC]
BKE22200 (Δ[gene|FA8D9AA0968365522DEFC05B277123FC96482044|cotD]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE22200 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATAAAATCCCCTTTCC, downstream forward: _UP4_TAGTATGGAAAACGTGCAGC
BKK22200 (Δ[gene|FA8D9AA0968365522DEFC05B277123FC96482044|cotD]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK22200 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATAAAATCCCCTTTCC, downstream forward: _UP4_TAGTATGGAAAACGTGCAGC
References
Reviews
Original Publications
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Time of last update: 2024-12-30 18:35:51
Author of last update: Jstuelk