cstA

cstA
168

similar to pyruvate transporter, carbon starvation-induced protein

Locus
BSU_28710
Molecular weight
64.19 kDa
Isoelectric point
8.66
Protein length
598 aaSequenceBlast
Gene length
1797 bpSequenceBlast
Function
uptake of pyruvate
Product
putative pyruvate transporter, carbon starvation-induced protein
Essential
no
Synonyms
cstA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1966 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,936,382 → 2,938,178
The protein
Catalyzed reaction/ biological activity
pyruvate:H+ symport PubMed
Protein family
peptide transporter carbon starvation (CstA) (TC 2.A.114) family (single member, according to UniProt)
Structure
P94532 (AlphaFold)
Localization
membrane (according to UniProt)
Expression and Regulation
Operons
Genes
cstA-ysfE
Description
PubMed
Regulation
repressed by glucose (3.4-fold) (CcpA) PubMed
Regulatory mechanism
CcpA: repression, PubMed, in ccpA regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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cstA→ysfE

2025-03-07 02:07:43

ghost

66

a577bd6c8262be9f7d56b55c40224b64a4df7fad

EBDDE99EDA22F3E4F409318C0A1210115C8AD2D2

Biological materials
Mutant
MGNA-B012 (cstA::erm), available at the NBRP B. subtilis, Japan
BKE28710 (ΔcstA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTTCTCCCATCCCCTTT,  downstream forward: _UP4_TAGAAGGACTATTGAAAATG
BKK28710 (ΔcstA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTTCTCCCATCCCCTTT,  downstream forward: _UP4_TAGAAGGACTATTGAAAATG
References
The E. coli homolog
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F93E473C06669DE604EC027236C79E5450F53720

Page visits: 2680

Time of last update: 2025-03-14 12:59:26

Author of last update: Jstuelk