xynP
168
beta-xyloside permease
locus
BSU_17570
Molecular weight
51.37 kDa
pI
8.58
function
xylan utilization
product
beta-xyloside permease
essential
no
synonyms
xynP, ynaJ
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2211 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,887,352 → 1,888,743
The protein
Protein family
[wiki|sodium:galactoside symporter (TC 2.A.2) family] (according to UniProt)
Structure
[PDB|4M64] (melibiose permease from Salmonella typhimurium, 31% identity) [pubmed|24389923]
[AF|P94488]
Paralogous protein(s)
[protein|B13F7C35FBD55C674E5B19836D32279E7C1A5520|gutP], [protein|59CD3E4C24326542D9C85BB6FE64FBF49869EB55|yjmB]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|F92925E2FDCFE6DDA3E87C7B541FE6A6CE5AABB8|xynP]-[gene|19CD9BF216953613CD2E0DFB99D4C6E92AAFAE5D|xynB]
description
[Pubmed|22383849]
regulation
carbon catabolite repression ([protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]) [Pubmed|9973552]
induction by xylose ([protein|AF4395D134485290F4AA307B48494FED39E52CD7|xylR]) [Pubmed|9973552]
regulatory mechanism
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|9973552], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
[protein|AF4395D134485290F4AA307B48494FED39E52CD7|xylR]: repression, [Pubmed|9973552], in [regulon|protein:AF4395D134485290F4AA307B48494FED39E52CD7|xylR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|9973552], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
MGNA-B107 (ynaJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1106 NBRP B. subtilis, Japan]
BKE17570 (Δ[gene|F92925E2FDCFE6DDA3E87C7B541FE6A6CE5AABB8|xynP]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE17570 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATTTCTCCCCTTTTCG, downstream forward: _UP4_TAAAAAAGAAAATAAACTGA
BKK17570 (Δ[gene|F92925E2FDCFE6DDA3E87C7B541FE6A6CE5AABB8|xynP]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK17570 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATTTCTCCCCTTTTCG, downstream forward: _UP4_TAAAAAAGAAAATAAACTGA
lacZ fusion
pGP417 (in [wiki|pAC7]), available in [wiki|Jörg Stülke]'s lab
References
Carbon catabolite repression
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Time of last update: 2024-12-20 18:26:05
Author of last update: Melvin.boenninger