rsbRB

rsbRB
168

part of the stressosome

locus
BSU_13200
Molecular weight
32.23 kDa
pI
4.79
Protein length
277 aaSequenceBlast
Gene length
834 bpSequenceBlast
function
control of [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB] activity
product
RsbR paralog
essential
no
synonyms
rsbRB, ispU, ykoB
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1366 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,387,206 → 1,388,039
The protein
Catalyzed reaction/ biological activity
negative regulator of [protein|6C5397BA5839E4DB25B370B39B6DA702147DA8B7|ytvA]-dependent light activation of the [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB] stress response [Pubmed|22287516]
[wiki|Domains]
[wiki|STAS domain] (aa 165-276) (according to UniProt)
Structure
[PDB|2MWG] ([protein|6C5397BA5839E4DB25B370B39B6DA702147DA8B7|ytvA], corresponds to aa 161 ... 273, 34% identity)
[AF|O34860]
Modification
phosphorylation on Thr-186 and probably also on Thr-220 by [protein|ADC52A22950736A0435AEEEC43F7407878786A81|rsbT] [Pubmed|21362065]
Paralogous protein(s)
[protein|5EEEDE60CE9E5CDAEBAB0E03AABDF1DF62F1F002|rsbRC], [protein|621357D1FB6AC1B0499732EFE226F982B26CE34E|rsbR], [protein|6C5397BA5839E4DB25B370B39B6DA702147DA8B7|ytvA], [protein|979D7A45EAD97C99015029400A85795061BAA367|rsbRD]
Expression and Regulation
Operons
genes
[gene|F53C527995909A1CFA72C7BF919DD10EE175C6D7|rsbRB]
description
[Pubmed|22383849]
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[gene|F53C527995909A1CFA72C7BF919DD10EE175C6D7|rsbRB]

2024-12-21 14:07:00

Jstuelk

57

2d93c21218eddb10ec595badaa15cd93d1f5adb9

8B22153DCC4CD6800CB49B836D3F2DED580102A4

Biological materials
Mutant
BKE13200 (Δ[gene|F53C527995909A1CFA72C7BF919DD10EE175C6D7|rsbRB]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE13200 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGACACTGCTCCTTTCCC,  downstream forward: _UP4_TAAAAAAATCCGCTATCTGT
BKK13200 (Δ[gene|F53C527995909A1CFA72C7BF919DD10EE175C6D7|rsbRB]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK13200 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATGACACTGCTCCTTTCCC,  downstream forward: _UP4_TAAAAAAATCCGCTATCTGT
References
36815589,15312768,17726680,17726680,17218307,20019076,28271471,28727759,36409125,38236030

F53C527995909A1CFA72C7BF919DD10EE175C6D7

Page visits: 4350

Time of last update: 2024-12-30 12:07:44

Author of last update: Jstuelk