cwlP
168
cell wall hydrolase of the SP-beta prophage region,
locus
BSU_21350
Molecular weight
252.01 kDa
pI
8.27
function
cell wall turnover
product
cell wall hydrolase
essential
no
synonyms
cwlP, yomI
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1196 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,249,154 → 2,256,011
The protein
Catalyzed reaction/ biological activity
hydrolyzes the peptidoglycan and cell wall of ''B. subtilis'' [Pubmed|20980266]
Protein family
transglycosylase Slt family (together with [protein|BD3C36B63C5D88FDBACFB18849F3DA863F38383F|cwlQ]) (according to UniProt)
[wiki|Domains]
contains soluble lytic transglycosylase (SLT) and peptidase M23 domains [Pubmed|20980266]
ten [wiki|TPR repeat|tetratrichopeptide repeats] (according to UniProt)
Structure
[AF|O31976]
[wiki|Localization]
cell membrane (according to Swiss-Prot)
Biological materials
Mutant
GP4480 (trpC2 Δ[gene|F43DC974DC71CB5F82DBD9B9D5ACEB49131772DB|cwlP]::neo), available in [wiki|Jörg Stülke]'s lab
BKE21350 (Δ[gene|F43DC974DC71CB5F82DBD9B9D5ACEB49131772DB|cwlP]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE21350 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAGTAAGAATCACTTCCTT, downstream forward: _UP4_TAAGAGTCTGCAAAAGCAGA
BKK21350 (Δ[gene|F43DC974DC71CB5F82DBD9B9D5ACEB49131772DB|cwlP]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK21350 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAGTAAGAATCACTTCCTT, downstream forward: _UP4_TAAGAGTCTGCAAAAGCAGA
References
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Time of last update: 2024-12-27 22:03:43
Author of last update: Robert.warneke