phrI
168
response regulator aspartate phosphatase (RapI) regulator
locus
BSU_05020
Molecular weight
4.10 kDa
pI
8.91
function
control of the transfer of the mobile genetic element ICEBs1
product
phosphatase (RapI) regulator
essential
no
synonyms
phrI
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms
This gene is a member of the following regulons
Gene
Coordinates
548,438 → 548,557
The protein
Catalyzed reaction/ biological activity
binds [protein|A208B4564A50D7BE2630DE40E8FAAF3C16236EE4|rapI] and inhibits its activity, this results in contiuned repression of the genes for the transfer of the mobile genetic element ICEBs1 by [protein|DD1C8F3A4809785BD6A6047D39B42AB2C605E161|immR] [Pubmed|17511812]
Protein family
[wiki|phr family] (according to UniProt)
Structure
[AF|O31492]
Expression and Regulation
Operons
genes
[gene|A208B4564A50D7BE2630DE40E8FAAF3C16236EE4|rapI]-[gene|F3E14B772A5DA9073ED806A9ADDD9B64F0DFDD5B|phrI]
description
[Pubmed|11466295]
regulation
induced at high cell density ([wiki|ComA]) [Pubmed|26582911]
regulatory mechanism
[protein|7832489F11F606BCF637EC23BAAB41AD10237EBB|comA]: activation, [Pubmed|26582911], in [regulon|protein:7832489F11F606BCF637EC23BAAB41AD10237EBB|comA regulon]
sigma factors
[protein|DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|sigH]: sigma factor, [Pubmed|11466295], in [regulon|protein:DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|sigH regulon]
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|11466295], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
genes
[gene|F3E14B772A5DA9073ED806A9ADDD9B64F0DFDD5B|phrI]
description
[Pubmed|11466295]
regulation
induced at high cell density ([wiki|ComA]) [Pubmed|26582911]
Biological materials
Mutant
BKE05020 (Δ[gene|F3E14B772A5DA9073ED806A9ADDD9B64F0DFDD5B|phrI]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE05020 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTACTTAAAATCACTGCT, downstream forward: _UP4_TAGCTTAGATAATTGGAAAA
BKK05020 (Δ[gene|F3E14B772A5DA9073ED806A9ADDD9B64F0DFDD5B|phrI]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK05020 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTACTTAAAATCACTGCT, downstream forward: _UP4_TAGCTTAGATAATTGGAAAA
References
Reviews
Original Publications
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Time of last update: 2024-12-19 12:00:33
Author of last update: Jstuelk