yxdJ
168
two-component response regulator ([wiki|OmpR family]), regulation of the ABC transporter [protein|8B4267532B9788AEB5EF39E2695C1FDA494C7055|yxdL]-[protein|4423383A3F6DAFDFA210F4BEEF7D8CBEC674DCEA|yxdM] in response to the cationic antimicrobial peptide, LL-37
locus
BSU_39660
Molecular weight
26.45 kDa
pI
4.94
function
resistance against toxic peptides
product
two-component response regulator ([wiki|OmpR family])
essential
no
synonyms
yxdJ, apeR
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0745 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
4,072,284 → 4,072,973
The protein
Protein family
[wiki|OmpR family] of two-component response regulators
[wiki|Domains]
[wiki|Response regulatory domain] (aa 3-116) (according to UniProt)
Structure
[PDB|5DCL] (NisR from Streptococcus agalactiae, 41% identity)
[AF|P42421]
Modification
phosphorylated by [protein|F5BB96607452AC38ECF66923DB8758C364FE2F46|yxdK] on an Asp residue
Expression and Regulation
Operons
genes
[gene|F3C5505E311E6DDABAFA87899F28CF6596CDBA63|yxdJ]-[gene|F5BB96607452AC38ECF66923DB8758C364FE2F46|yxdK]
description
[Pubmed|10746760]
Biological materials
Mutant
MGNA-B702 (yxdJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1701 NBRP B. subtilis, Japan]
BKE39660 (Δ[gene|F3C5505E311E6DDABAFA87899F28CF6596CDBA63|yxdJ]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE39660 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAACTGAACCACTCCCGTT, downstream forward: _UP4_GGCTACCAGCTGAGGGCGCA
BKK39660 (Δ[gene|F3C5505E311E6DDABAFA87899F28CF6596CDBA63|yxdJ]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK39660 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAACTGAACCACTCCCGTT, downstream forward: _UP4_GGCTACCAGCTGAGGGCGCA
References
Reviews
Original Publications
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Time of last update: 2024-12-21 03:59:41
Author of last update: Jstuelk