ypeB
168
[wiki|germination] protein, essential for [protein|92E50EF57FFCB22563B3C3A73B0885CCED8E9692|sleB] assembly in spores
locus
BSU_22920
Molecular weight
51.02 kDa
pI
6.31
function
assembly of [protein|92E50EF57FFCB22563B3C3A73B0885CCED8E9692|sleB]
product
[wiki|germination] protein
essential
no
synonyms
ypeB, joeB, yzuA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG5914 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,397,765 → 2,399,117
The protein
Protein family
ypeB family (single member, according to UniProt)
[wiki|Domains]
has a membrane-spanning domain in the N-terminal region [Pubmed|23335419]
Structure
[PDB|5BOI] (C-terminal domain of B. megaterium YpeB, aa 211-450, 53% identity) [pubmed|26219275]
[AF|P38490]
[wiki|Localization]
outer surface of the inner spore membrane [Pubmed|23335419]
Expression and Regulation
Operons
genes
[gene|92E50EF57FFCB22563B3C3A73B0885CCED8E9692|sleB]-[gene|F17F7F4330F1B3C609B8E32581DA6EAC6C69752B|ypeB]
description
[Pubmed|15699190,10197998]
regulation
expressed late during sporulation in the forespore ([protein|search|SigG]) [Pubmed|15699190,10197998]
sigma factors
[protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG]: sigma factor, [Pubmed|15699190,10197998], in [regulon|protein:5F24258282F3166B7696B9E9ABC1706E4D06C944|sigG regulon]
Biological materials
Mutant
MGNA-A400 (ypeB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/400 NBRP B. subtilis, Japan]
BKE22920 (Δ[gene|F17F7F4330F1B3C609B8E32581DA6EAC6C69752B|ypeB]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE22920 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTATCACACCTCTTTTT, downstream forward: _UP4_TAAAAACAGGAGGAAAGGAC
BKK22920 (Δ[gene|F17F7F4330F1B3C609B8E32581DA6EAC6C69752B|ypeB]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK22920 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTATCACACCTCTTTTT, downstream forward: _UP4_TAAAAACAGGAGGAAAGGAC
References
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Time of last update: 2024-12-21 10:05:35
Author of last update: Jstuelk