yetJ
168
pH-dependent calcium leak
locus
BSU_07200
Molecular weight
23.68 kDa
pI
9.14
function
export of calcium, homeostasis
product
pH-dependent calcium leak
essential
no
synonyms
yetJ
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0670 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
787,992 → 788,636
The protein
Protein family
BI1 family (single member, according to UniProt)
Structure
[PDB|4PGU] [Pubmed|24904158]
[PDB|6NQ7] (lipidic cubic phase) [Pubmed|30930064]
[PDB|6NQ8] (D171E mutant) [Pubmed|30930064]
[PDB|6NQ9] (D195E mutant) [Pubmed|30930064]
[AF|O31539]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|F0A217DB65ED7A7539F775FEBC5D88718B4958BD|yetJ]-[gene|9B8857B4493AD36A2395372B00273244D291BBA7|yetK]
description
[Pubmed|22383849]
genes
[gene|F0A217DB65ED7A7539F775FEBC5D88718B4958BD|yetJ]
description
[Pubmed|22383849]
genes
[gene|1F2E7B30C04E8C58DDC3583A9C912BD480E979F7|yezD]-[gene|F0A217DB65ED7A7539F775FEBC5D88718B4958BD|yetJ]-[gene|9B8857B4493AD36A2395372B00273244D291BBA7|yetK]
description
[Pubmed|22383849]
genes
[gene|1F2E7B30C04E8C58DDC3583A9C912BD480E979F7|yezD]-[gene|F0A217DB65ED7A7539F775FEBC5D88718B4958BD|yetJ]
description
[Pubmed|22383849]
regulatory mechanism
[protein|50930C56C27D22715620A350220E3C56ADB41020|cymR]: repression, [Pubmed|16885442], in [regulon|protein:50930C56C27D22715620A350220E3C56ADB41020|cymR regulon]
Biological materials
Mutant
GP4470 (trpC2 Δ[gene|F0A217DB65ED7A7539F775FEBC5D88718B4958BD|yetJ]::neo), available in [wiki|Jörg Stülke]'s lab
MGNA-B461 (yetJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1460 NBRP B. subtilis, Japan]
BKE07200 (Δ[gene|F0A217DB65ED7A7539F775FEBC5D88718B4958BD|yetJ]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE07200 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCAAAAATCCTCCTAA, downstream forward: _UP4_GGCATTTTGAGCAGTGATGA
BKK07200 (Δ[gene|F0A217DB65ED7A7539F775FEBC5D88718B4958BD|yetJ]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK07200 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCAAAAATCCTCCTAA, downstream forward: _UP4_GGCATTTTGAGCAGTGATGA
References
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Time of last update: 2024-11-21 03:42:31
Author of last update: Jstuelk